Evidence map›Paper›PMID 34171089›Full record

ArticleThe journals of gerontology. Series A, Biological sciences and medical sciences2022

APOE e4 Genotypes Increase Risk of Delirium During COVID-19-Related Hospitalizations: Evidence From a Large UK Cohort.

Chia-Ling Kuo, Luke C Pilling, Janice L Atkins, Richard H Fortinsky, George A Kuchel, David Melzer

Open access · hybridAbstract read
In one paragraph

Article in The journals of gerontology. Series A, Biological sciences and medical sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Apolipoprotein E and viral infection: Risks and Mechanisms.Molecular therapy. Nucleic acids · 2023
    Review
  4. Article
  5. Article
  6. Article
  7. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Chia-Ling KuoConnecticut Convergence Institute for Translation in Regenerative Engineering, University of Connecticut Health, Farmington, USA.ORCID 0000-0003-4452-2380
Luke C PillingEpidemiology and Public Health Group, University of Exeter Medical School, UK.ORCID 0000-0002-3332-8454
Janice L AtkinsEpidemiology and Public Health Group, University of Exeter Medical School, UK.ORCID 0000-0003-4919-9068
Richard H FortinskyCenter on Aging, University of Connecticut Health, Farmington, USA.
George A KuchelCenter on Aging, University of Connecticut Health, Farmington, USA.
David MelzerEpidemiology and Public Health Group, University of Exeter Medical School, UK.
UConn Health · USUniversity of Exeter · GB

Funding

Understanding the role of ApoE2 in longevity and age-related diseases and conditions using 500,000 UK Biobank participantsR21AG060018 · NIA · UNIVERSITY OF CONNECTICUT SCH OF MED/DNT · PI KUO, CHIA-LING · 2018 to 2020
$434k
NIA NIH HHS R21 AG060018
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Apolipoprotein E4COVID-19DeliriumAllelesApolipoproteins EGenotypeHospitalizationHumansUnited KingdomApolipoprotein E4Apolipoproteins E

Identifiers

PMID34171089
PMCPMC8344705
OpenAlexW3175148583

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.