Evidence map›Paper›PMID 34171072›Full record

ArticleRomanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie

Calcium fructoborate coating of titanium-hydroxyapatite implants by chemisorption deposition improves implant osseointegration in the femur of New Zealand White rabbit experimental model.

Renata Maria Văruţ, Petru Răzvan Melinte, Andreea Silvia Pîrvu, Oana Gîngu, Gabriela Sima, Carmen Nicoleta Oancea, Alina Cristina Teişanu, Gheorghe Drăgoi, Andrei Biţă, Horia Octavian Manolea and 4 more

Open access · diamondAbstract read
In one paragraph

Article in Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. New Insights into Boron Essentiality in Humans and Animals.International journal of molecular sciences · 2022
    Review
  4. Boron-containing compounds in Dentistry: a narrative review.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Review
  5. Osseointegration evaluation of an experimental bone graft material based on hydroxyapatite, reinforced with titanium-based particles.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 1 institution in 1 country.

Renata Maria VăruţDepartment of Biochemistry, BioBoron Research Institute, S.C. Natural Research S.R.L., Podari, Dolj County, Romania; romulus_ion@yahoo.com.
Petru Răzvan Melinte
Andreea Silvia Pîrvu
Oana Gîngu
Gabriela Sima
Carmen Nicoleta Oancea
Alina Cristina Teişanu
Gheorghe Drăgoi
Andrei Biţă
Horia Octavian Manolea
Ioana Mitruţ
Otilia Constantina Rogoveanu
Ion Scorei Romulus
Johny Neamţu
University of Medicine and Pharmacy of Craiova · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe identification of biocomposites that improve cell adhesion and reduce bone integration time is a great challenge for implantology and bone reconstruction.

aimOur aim was to evaluate a new method of chemisorption deposition (CD) for improving the biointegration of hydroxyapatite-coated titanium (HApTi) implants. CD method was used to prepare a calcium fructoborate (CaFb) coating on a HApTi (HApTiCaFb) implant followed by evaluation of histological features related to bone healing at the interface of a bioceramic material in an animal model.

methodsThe coating composition was investigated by high-performance thin-layer chromatography/mass spectrometry. The surface morphology of the coating was studied by scanning electron microscopy (SEM), before and after the in vitro study. We implanted two types of bioceramic cylinders, HApTi and HApTiCaFb, in the femur of 10 New Zealand White (NZW) rabbits.

resultsThe release of CaFb from HApTiCaFb occurred rapidly within the first three days after phosphate-buffered saline immersion; there was then a linear release for up to 14 days. SEM analysis showed similar morphology and particle size diameter for both implants. Around the porous HApTiCaFb implant, fibrosis and inflammation were not highlighted.

conclusionsEasily applied using CD method, CaFb coatings promote HApTi implant osseointegration in the femur of NZW rabbits.

Indexed as

Dental ImplantsOsseointegrationAnimalsBoratesCoated Materials, BiocompatibleDurapatiteFemurFructoseImplants, ExperimentalMicroscopy, Electron, ScanningModels, TheoreticalRabbitsSurface PropertiesTitaniumBoratescalcium fructoborateCoated Materials, BiocompatibleDental ImplantsDurapatiteFructoseTitanium

Identifiers

PMID34171072
PMCPMC8343473
OpenAlexW3175235007

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.