Evidence map›Paper›PMID 34171051›Full record

ReviewRomanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie

Pediatric nonalcoholic fatty liver disease - a changing diagnostic paradigm.

Laura Mihaela Trandafir, Otilia Elena Frasinariu, Maria Magdalena Leon-Constantin, Ştefan Chiriac, Mioara Florentina Trandafirescu, Ingrith Crenguţa Miron, Alina Costina Luca, Alin Constantin Iordache, Elena Cojocaru

Open access · diamondAbstract readReview
In one paragraph

Review in Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Laura Mihaela TrandafirFirst Medical Department, Grigore T. Popa University of Medicine and Pharmacy, Iaşi, Romania; leon_mariamagdalena@yahoo.com, stefannchiriac@yahoo.com.
Otilia Elena Frasinariu
Maria Magdalena Leon-Constantin
Ştefan Chiriac
Mioara Florentina Trandafirescu
Ingrith Crenguţa Miron
Alina Costina Luca
Alin Constantin Iordache
Elena Cojocaru
Grigore T. Popa University of Medicine and Pharmacy · RO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Worldwide, nonalcoholic fatty liver disease (NAFLD) has emerged as the leading cause of chronic liver disease in children and adolescents, but also as a real public health issue. Over the last decades, the increase in the rates of obesity and overweight in children has led to the increase in the worldwide prevalence of pediatric NAFLD. Detection of a hyperechoic appearance of the liver at ultrasounds or elevated levels of transaminases, identified during a routine control in children, suggests NAFLD. The disorder can be diagnosed with either non-invasive strategies or through liver biopsy, which further allows the identification of specific histological aspects, distinct from those found in adults. Since NAFLD is a clinically heterogeneous disease, there is an imperative need to identify noninvasive biomarkers and screening techniques for early diagnosis in children, in order to prevent metabolic and cardiovascular complications later in adulthood. This review emphasizes the main diagnosis tools in pediatric NAFLD, a systemic disorder with multifactorial pathogenesis and varying clinical manifestations.

Indexed as

Non-alcoholic Fatty Liver DiseaseAdolescentAdultChildHumansLiver CirrhosisObesityUltrasonography

Identifiers

PMID34171051
PMCPMC8343491
OpenAlexW3173338647

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.