Evidence map›Paper›PMID 34170948›Full record

SynthesisPloS one2021

A systematic review of the association between perinatal depression and cognitive development in infancy in low and middle-income countries.

Matthew Bluett-Duncan, M Thomas Kishore, Divya M Patil, Veena A Satyanarayana, Helen Sharp

Abstract readSystematic Review
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in PloS one, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Matthew Bluett-DuncanDepartment of Primary Care and Mental Health, Institute of Population Health, University of Liverpool, United Kingdom.ORCID 0000-0002-7539-6746
M Thomas KishoreDepartment of Clinical Psychology, National Institute of Mental Health and Neurosciences, Bengaluru, India.
Divya M PatilDepartment of Epidemiology, School of Public Health, University of Washington, Washington, DC, United States of America.
Veena A SatyanarayanaDepartment of Clinical Psychology, National Institute of Mental Health and Neurosciences, Bengaluru, India.
Helen SharpDepartment of Primary Care and Mental Health, Institute of Population Health, University of Liverpool, United Kingdom.

Funding

Medical Research Council MR/N000870/1Medical Research Council MR/S036466/1
6 · The paper itself

Abstract

The association between perinatal depression and infant cognitive development has been well documented in research based in high-income contexts, but the literature regarding the same relationship in low and middle-income countries (LMICs) is less developed. The aim of this study is to systematically review what is known in this area in order to inform priorities for early intervention and future research in LMICs. The review protocol was pre-registered on Prospero (CRD42018108589) and relevant electronic databases were searched using a consistent set of keywords and 1473 articles were screened against the eligibility criteria. Sixteen articles were included in the review, seven focusing on the antenatal period, eight on the postnatal period, and one which included both. Five out of eight studies found a significant association between antenatal depression (d = .21-.93) and infant cognitive development, while four out of nine studies found a significant association with postnatal depression (d = .17-.47). Although the evidence suggests that LMICs should prioritise antenatal mental health care, many of the studies did not adequately isolate the effects of depression in each period. Furthermore, very few studies explored more complex interactions that may exist between perinatal depression and other relevant factors. More high-quality studies are needed in LMIC settings, driven by current theory, that test main effects and examine moderating or mediating pathways to cognitive development.

Indexed as

Child DevelopmentCognitionDepression, PostpartumAdultDeveloping CountriesFemaleHumansInfantInfant, NewbornMalePregnancy

Identifiers

PMID34170948
PMCPMC8232443

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.