ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2021
Mastication, swallowing, and salivary flow in patients with head and neck cancer: objective tests versus patient-reported outcomes.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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Who cites it
13 citing papers in PubMed, 23 citations in OpenAlex.
- Photobiomodulation for restoring salivary flow after radiotherapy in head and neck cancer: a randomised placebo-controlled trial.BMC oral health · 2025Trial
- Full-Mouth Digital Dental Rehabilitation Under General Anesthesia in a Post-Treatment Intraoral Squamous Cell Carcinoma Patient: A Case Report.Healthcare (Basel, Switzerland) · 2025Article
- Functional assessment of cancer therapy - head & neck (FACT-HN) translation and validation in Serbian.Scientific reports · 2025Article
- Validity and Responsiveness of Measuring Facial Swelling With 3D Stereophotogrammetry in Patients After Bilateral Sagittal Split Osteotomy-A Prospective Clinimetric Study.International journal of biomedical imaging · 2025Article
- Association between objective measures of oral health and salivary gland irradiation with patient-reported outcomes following head and neck radiation therapy.Head & neck · 2024Article
- Global assessment of swallow function (GASF) following VMAT radiotherapy for head and neck squamous cell carcinoma.Technical innovations & patient support in radiation oncology · 2024Article
- Comparison of Submental Surface Electromyography during Dry Swallow between Irradiated Head and Neck Cancer Survivors and Normal Individuals.Folia phoniatrica et logopaedica : official organ of the International Association of Logopedics and Phoniatrics (IALP) · 2024Article
- Oral functioning after open versus closed treatment of unilateral condylar neck or base fractures: A two-centre controlled clinical trial.Journal of oral rehabilitation · 2023Article
- Functioning of the Masticatory System in Patients with an Alloplastic Total Temporomandibular Joint Prostheses Compared with Healthy Individuals: A Pilot Study.Life (Basel, Switzerland) · 2022Article
- The course of swallowing problems in the first 2 years after diagnosis of head and neck cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Article
- Comparison of Objective Measures of Trismus and Salivation With Patient-Reported Outcomes Following Treatment for Head and Neck Cancer.JAMA otolaryngology-- head & neck surgery · 2022Article
- Implant-based dental rehabilitation in head and neck cancer patients after maxillofacial reconstruction with a free vascularized fibula flap: the effect on health-related quality of life.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Article
- From Radiation to Weight Loss: The Self-perpetuating Cycle of Oral Mucositis: Insights from a Pilot Institutional Study.Annals of maxillofacial surgeryArticle
Corrections and comments
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Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
Abstract
purposeBefore and after treatment for head and neck cancer (HNC), many patients have problems with mastication, swallowing, and salivary flow. The aim of this study was to investigate the association between objective test outcomes of mastication, swallowing, and salivary flow versus patient-reported outcomes (PROs) measuring mastication-, swallowing-, and salivary flow-related quality of life.
methodsData of the prospective cohort "Netherlands Quality of Life and Biomedical Cohort Study" was used as collected before treatment, and 3 and 6 months after treatment. Spearman's rho was used to test the association between objective test outcomes of the mixing ability test (MAT) for masticatory performance, the water-swallowing test (WST) for swallowing performance, and the salivary flow test versus PROs (subscales of the EORTC QLQ-H&N35, Swallow Quality of Life questionnaire (SWAL-QoL-NL) and Groningen Radiation-Induced Xerostomia (GRIX)).
resultsData of 142 patients were used, and in total, 285 measurements were performed. No significant correlations were found between the MAT or WST and subscales of the EORTC QLQ-H&N35. Significant but weak correlations were found between the MAT or WST and 4 subscales of the SWAL-QoL-NL. Weak to moderate correlations were found between the salivary flow test and GRIX at 3 and 6 months after treatment, with the highest correlation between salivary flow and xerostomia during the day (Spearman's rho = - 0.441, p = 0.001).
conclusionThe association between objective test outcomes and PROs is weak, indicating that these outcome measures provide different information about masticatory performance, swallowing, and salivary flow in patients with HNC.
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