Evidence map›Paper›PMID 34170392›Full record

Trial reportEuropean journal of nutrition2021

Impact of dietary supplementation with resistant dextrin (NUTRIOSE

Mark R Hobden, Daniel M Commane, Laetitia Guérin-Deremaux, Daniel Wils, Clementine Thabuis, Agustin Martin-Morales, Saskia Wolfram, Antonio Dìaz, Sineaid Collins, Ines Morais and 3 more

Erratum issued Registry-linked trialOpen access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in European journal of nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT02041975 (Investigating the Effects of Prebiotic-based Snacks on Perceived Feelings of 'Satisfaction' and on the Balance of Bacteria in the Human Gut), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.9field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02041975 nacompletednot on this map

Investigating the Effects of Prebiotic-based Snacks on Perceived Feelings of 'Satisfaction' and on the Balance of Bacteria in the Human Gut (NutriSAT)

TypeinterventionalSponsorUniversity of ReadingRan2013 to 2016Enrolled47ConditionsObesityArmsNutriose FB06, Placebo
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Mark R HobdenDepartment of Food and Nutritional Sciences, School of Chemistry, Pharmacy and Food, The University of Reading, Reading, UK.
Daniel M CommaneFaculty of Health and Life Sciences, Northumbria University, Newcastle, UK. daniel.commane@northumbria.ac.uk.ORCID http://orcid.org/0000-0002-0154-8540
Laetitia Guérin-DeremauxDepartment of Nutrition and Health, Roquette, Lestrem, France.
Daniel WilsDepartment of Nutrition and Health, Roquette, Lestrem, France.
Clementine ThabuisDepartment of Nutrition and Health, Roquette, Lestrem, France.
Agustin Martin-MoralesDepartment of Food and Nutritional Sciences, School of Chemistry, Pharmacy and Food, The University of Reading, Reading, UK.
Saskia WolframDepartment of Food and Nutritional Sciences, School of Chemistry, Pharmacy and Food, The University of Reading, Reading, UK.
Antonio DìazDepartment of Food and Nutritional Sciences, School of Chemistry, Pharmacy and Food, The University of Reading, Reading, UK.
Sineaid CollinsDepartment of Food and Nutritional Sciences, School of Chemistry, Pharmacy and Food, The University of Reading, Reading, UK.
Ines MoraisDepartment of Food and Nutritional Sciences, School of Chemistry, Pharmacy and Food, The University of Reading, Reading, UK.
Ian R RowlandDepartment of Food and Nutritional Sciences, School of Chemistry, Pharmacy and Food, The University of Reading, Reading, UK.
Glenn R GibsonDepartment of Food and Nutritional Sciences, School of Chemistry, Pharmacy and Food, The University of Reading, Reading, UK.
Orla B KennedyDepartment of Food and Nutritional Sciences, School of Chemistry, Pharmacy and Food, The University of Reading, Reading, UK.
University of Reading · GBRoquette Frères (France) · FRNorthumbria University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeResistant dextrin (RD) supplementation has been shown to alter satiety, glycaemia, and body weight, in overweight Chinese men; however, there are limited data on its effects in other demographic groups. Here, we investigated the effects of RD on satiety in healthy adults living in the United Kingdom.

methods20 normal weight and 16 overweight adults completed this randomised controlled cross-over study. Either RD (14 g/day NUTRIOSE

resultsChronic supplementation with RD was associated with higher fasted satiety scores at day 14 (P = 0.006) and day 28 (P = 0.040), compared to control. RD also increased satiety after the mid-morning intervention drink, but it was associated with a reduction in post-meal satiety following both the lunch and evening meals (P < 0.01). The glycaemic response to the mid-morning intervention drink (0-30 min) was attenuated following RD supplementation (P < 0.01). Whilst not a primary endpoint we also observed lower systolic blood pressure at day 14 (P = 0.035) and 28 (P = 0.030), compared to day 1, following RD supplementation in the normal weight group. Energy intake and anthropometrics were unaffected.

conclusionsRD supplementation modified satiety and glycaemic responses in this cohort, further studies are required to determine longer-term effects on body weight control and metabolic markers. CLINICALTRIALS. GOV REGISTRATION: NCT02041975 (22/01/2014).

Indexed as

DextrinsSatiety ResponseAdultBlood GlucoseCross-Over StudiesDietary SupplementsEnergy IntakeHumansMaleSatiationBlood GlucoseDextrinsNUTRIOSEAppetiteGlycaemiaObesityPrebioticResistant dextrinSatiety

Identifiers

PMID34170392
PMCPMC8572182
OpenAlexW3175034163

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.