ReviewDer Urologe. Ausg. A2021
[non-metastasised clincial stage I testicular germ cell tumours : Patient information, suitability and limitations of surveillance].
Review in Der Urologe. Ausg. A, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Authors and funding
2 authors.
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Abstract
backgroundSurveillance is the most frequently used treatment option in testicular germ cell tumour (TGCT) patients in nonmetastasised clinical stage I (cSI).
objectivesPresentation of indications for surveillance, the process of individual patient's advice and the limitations of surveillance. MATERIALS AND
methodsAn overview of the current literature is given, including basic research, systemic reviews and expert recommendations. Basic principles are illustrated by case reports.
resultsThe risk of progression for cSI TGCT patients under surveillance is 5-30% for seminomas and 15-50% for nonseminomas. Surveillance is the preferred treatment option in seminoma and low-risk nonseminoma without lymphovascular invasion. Patients should be informed concerning the individual risk of progression, the possibilities of adjuvant therapy, side effects of adjuvant therapy, the kind of therapy in case of progression and the cure rate. A high risk of progression, psychological issues and malcompliance are important limitations of surveillance.
conclusionBy thoroughly considering the limitations of surveillance, cSI TGCT patients can be safely treated with surveillance.
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Registered trials
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