ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2021
Hot flashes, insomnia, and the reproductive stages: a cross-sectional observation of women from the EPISONO study.
Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 24 citations in OpenAlex.
- Pooled it
- Hot flashes and sleep disruption in a randomized trial in menopausal women.American journal of obstetrics and gynecology · 2025Trial
- Subjective menopausal hot flashes in sleep disturbance: does the timing of hot flashes matter?Menopause (New York, N.Y.) · 2026Article
- Evaluating perioperative self-reported sleep quality in patients with a gynecologic malignancy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Review
- Menopause-Related Changes in Sleep and the Associations with Cardiometabolic Health: A Narrative Review.Healthcare (Basel, Switzerland) · 2025Review
- How do phases of the menstrual cycle affect sleep? A polysomnographic study of the EPISONO database.Sleep & breathing = Schlaf & Atmung · 2024Article
- Association between sleep duration and depression in menopausal women: a population-based study.Frontiers in endocrinology · 2024Article
- Insomnia as a Risk Factor for Substance Use Disorders in Women.Sleep medicine clinics · 2023Review
- A Review of Hormone and Non-Hormonal Therapy Options for the Treatment of Menopause.International journal of women's health · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 1 institution in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
STUDY
objectivesTo investigate the association of hot flashes and insomnia in women in premenopause and postmenopause.
methodsThe study was performed using data from the São Paulo Epidemiological Sleep Study. Women in premenopause were classified as having regular menstrual cycles, being anovulatory, or using hormonal contraceptives. Women in menopause were classified as being in perimenopause, early postmenopause, or late postmenopause. Women reporting frequent insomnia symptoms and relevant daytime complaints were classified as having insomnia disorder. Polysomnography alterations suggestive of insomnia were also identified.
resultsThe frequency of hot flashes was 42% among women in postmenopause (mainly in early postmenopause) and 9% among women in premenopause (mainly anovulatory;
conclusionsHot flashes are associated with insomnia and polysomnography alterations suggestive of insomnia. The prevalence of hot flashes among women with insomnia disorder is especially high among women in late postmenopause. CITATION: Hachul H, Castro LS, Bezerra AG, et al. Hot flashes, insomnia, and the reproductive stages: a cross-sectional observation of women from the EPISONO study.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.