Evidence map›Paper›PMID 34170223›Full record

ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2021

Assessment of self-reported and objective daytime sleepiness in adult-onset myotonic dystrophy type 1.

Valeria A Sansone, Paola Proserpio, Luca Mauro, Andrea Lizio Biostat, Erica Frezza, Andrea Lanza, Paola Rogliani, Gabriella Pezzuto, Elisa Falcier, Carola Ferrari Aggradi and 17 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. A systematic review of the frequency of sleep evaluations, sleep disorders, and treatments among individuals with muscular dystrophy.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2026
    Pooled it
  2. Article
  3. Article
  4. Review
  5. Article
  6. Subjective-objective sleepiness discrepancy in adult-onset myotonic dystrophy type 1.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

27 authors at 6 institutions in 2 countries.

Valeria A SansoneNeurorehabilitation Unit, University of Milan, Milan, Italy.
Paola ProserpioSleep Medicine Center, Dept. Neuroscience, Niguarda Hospital, Milan, Italy.
Luca MauroThe NEMO Clinical Center, Milan, Italy.
Andrea Lizio BiostatThe NEMO Clinical Center, Milan, Italy.
Erica FrezzaDepartment of Neurology, Tor Vergata University of Rome, Rome, Italy.
Andrea LanzaSleep Medicine Center, Dept. Neuroscience, Niguarda Hospital, Milan, Italy.
Paola RoglianiDepartment of Respiratory Diseases, Tor Vergata University of Rome, Rome, Italy.
Gabriella PezzutoDepartment of Respiratory Diseases, Tor Vergata University of Rome, Rome, Italy.
Elisa FalcierThe NEMO Clinical Center, Milan, Italy.
Carola Ferrari AggradiThe NEMO Clinical Center, Milan, Italy.
Alice PirolaThe NEMO Clinical Center, Milan, Italy.
Fabrizio RaoThe NEMO Clinical Center, Milan, Italy.
Elisabetta RomaThe NEMO Clinical Center, Milan, Italy.
Claudia GalluzziDepartment of Neurology, Tor Vergata University of Rome, Rome, Italy.
Matteo SpanettaDepartment of Neurology, Tor Vergata University of Rome, Rome, Italy.
Federica CattaneoSleep Medicine Center, Dept. Neuroscience, Niguarda Hospital, Milan, Italy.
Annalisa RubinoSleep Medicine Center, Dept. Neuroscience, Niguarda Hospital, Milan, Italy.
Elio Clemente AgostoniSleep Medicine Center, Dept. Neuroscience, Niguarda Hospital, Milan, Italy.
Federica AmicoSleep Medicine Center, Dept. Neuroscience, Niguarda Hospital, Milan, Italy.
Alice ZanoliniThe NEMO Clinical Center, Milan, Italy.
Francesca IzziDepartment of Neurology, Tor Vergata University of Rome, Rome, Italy.
Giulia GrecoDepartment of Neurology, Tor Vergata University of Rome, Rome, Italy.
Andrea RomigiIRCCS Neuromed Istituto Neurologico Mediterraneo, Pozzilli (IS), Rome, Italy.
Claudio LiguoriDepartment of Neurology, Tor Vergata University of Rome, Rome, Italy.
Lino NobiliChild Neuropsychiatry Unit, IRCCS Istituto G. Gaslini, Genoa, Italy.
Fabio PlacidiDepartment of Neurology, Tor Vergata University of Rome, Rome, Italy.
Roberto MassaDepartment of Neurology, Tor Vergata University of Rome, Rome, Italy.
University of Rome Tor Vergata · ITCentro Clinico Nemo · ITAzienda Socio Sanitaria Territoriale Grande Ospedale Metropolitano Niguarda · ITIn-Q-Tel · USIstituti di Ricovero e Cura a Carattere Scientifico · ITIstituto Neurologico Mediterraneo · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

objectivesExcessive daytime sleepiness (EDS) in myotonic dystrophy type 1 is mostly of central origin but it may coexist with sleep-related breathing disorders. However, there is no consensus on the sleep protocols to be used, assessments vary, and only a minority of patients are regularly tested or are on treatment for EDS. Our study presents data on self-reported and objective EDS in adult-onset myotonic dystrophy type 1.

methodsSixty-three patients with adult-onset DM1 were subjected to EDS-sleep assessments (polysomnography, Multiple Sleep Latency Test, Epworth Sleepiness Scale). Correlation coefficients were computed to assess the relationship between sleep and sleepiness test results, fatigue, and quality of life.

results33% and 48% of patients had EDS based, respectively, on the Epworth Sleepiness Scale and the Multiple Sleep Latency Test, with a low concordance between these tests (k = 0.19). Thirteen patients (20%) displayed 2 or more sleep-onset rapid eye movement periods on Multiple Sleep Latency Test. Patients having EDS by Multiple Sleep Latency Test had a shorter disease duration (

conclusionsEDS test results are contradictory, making treatment options difficult. Combining quantitative tests and self-reported scales may facilitate physicians in planning EDS care with patients and families. CITATION: Sansone VA, Proserpio P, Mauro L, et al. Assessment of self-reported and objective daytime sleepiness in adult-onset myotonic dystrophy type 1.

Indexed as

Disorders of Excessive SomnolenceMyotonic DystrophyAdultHumansPolysomnographyQuality of LifeSelf ReportEpworth Sleepiness Scaleexcessive daytime sleepinessMultiple Sleep Latency Testmyotonic dystrophy type 1polysomnography

Identifiers

PMID34170223
PMCPMC8726376
OpenAlexW3173558579

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.