Evidence map›Paper›PMID 34170220›Full record

ArticleJournal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine2021

Prevalence of sleepiness and associations with quality of life in patients with sleep apnea in an online cohort.

Lindsey J Wanberg, Rebecca E Rottapel, Michelle L Reid, Suzanne M Bertisch, Morgan Bron, Vishesh K Kapur, Shay Bujanover, Zinta Harrington, Jessie P Bakker, Sogol Javaheri and 6 more

Open access · bronzeAbstract read
In one paragraph

Article in Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 14 citations in OpenAlex.

  1. Trial
  2. Clinical significance of sleepiness: an American Academy of Sleep Medicine position statement.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025
    Article
  3. Article
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  8. Comorbid obstructive sleep apnea and insomnia and its associations with mood and diabetes-related distress in type 2 diabetes mellitus.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 7 institutions in 2 countries.

Lindsey J WanbergDivision of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, Massachusetts.
Rebecca E RottapelDivision of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, Massachusetts.
Michelle L ReidDivision of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, Massachusetts.
Suzanne M BertischDivision of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, Massachusetts.
Morgan BronJazz Pharmaceuticals, Inc., Palo Alto, California.
Vishesh K KapurDivision of Pulmonary, Critical Care, and Sleep Medicine, Department of Medicine, University of Washington, Seattle, Washington.
Shay BujanoverJazz Pharmaceuticals, Inc., Palo Alto, California.
Zinta HarringtonUniversity of New South Wales, Sydney, Australia.
Jessie P BakkerDivision of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, Massachusetts.
Sogol JavaheriDivision of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, Massachusetts.
Mark HansonSleep Apnea Patient-Centered Outcomes Network, Boston, Massachusetts.
Kathleen FigetakisSleep Apnea Patient-Centered Outcomes Network, Boston, Massachusetts.
Kathy PageSleep Apnea Patient-Centered Outcomes Network, Boston, Massachusetts.
Sherry HanesSleep Apnea Patient-Centered Outcomes Network, Boston, Massachusetts.
Kathleen F VillaJazz Pharmaceuticals, Inc., Palo Alto, California.
Susan RedlineDivision of Sleep and Circadian Disorders, Brigham and Women's Hospital, Boston, Massachusetts.
Patient-Centered Outcomes Research Institute · USBrigham and Women's Hospital · USCircadian (United States) · USJazz Pharmaceuticals (United States) · USHarvard University · USUniversity of Washington · USUNSW Sydney · AU

Funding

Phenotypic and Molecular Signatures for Sleep Apnea and Related MorbiditiesR35HL135818 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI REDLINE, SUSAN S. · 2017 to 2023
$7.2M
NHLBI NIH HHS R35 HL135818
6 · The paper itself

Abstract

STUDY

objectivesExcessive daytime sleepiness (EDS) is a treatment target for many patients with obstructive sleep apnea (OSA). We aimed to understand the prevalence, risk factors, and quality of life associated with EDS in a nonclinical, "real world" sample of patients with OSA.

methodsCross-sectional survey of patients with OSA participating in an online peer support community, assessing demographics, comorbidities, treatment, and quality of life. Differences in those with and without EDS (Epworth Sleepiness Scale > and ≤ 10) were assessed.

resultsThe sample (n = 422) was 54.2% male, 65.9% were ≥ 55 years, and 43.3% reported sleeping ≤ 6 hours/night. EDS was identified among 31.0% of respondents and 51.7% reported sleepiness as a precipitating factor for seeking initial OSA treatment. EDS was more prevalent in individuals reporting asthma, insomnia symptoms, positive airway pressure (PAP) use less than 6 hours/night on ≥ 5 nights/week, or sleep duration < 6 hours/night. After adjusting for demographics and comorbidities, patients with EDS reported poorer mental and physical health and well-being, lower disease-specific functional status, more activity and work impairment, and more driving impairment (

conclusionsThese "real world" data suggest that patients seeking online OSA support experience a high prevalence of EDS, which was associated with poorer quality of life and worse functional status. Associations persisted among respondents with high self-reported PAP-therapy adherence, potentially driving these individuals to seek online support for sleepiness-related symptoms. CITATION: Wanberg LJ, Rottapel RE, Reid ML, et al. Prevalence of sleepiness and associations with quality of life in patients with sleep apnea in an online cohort.

Indexed as

Disorders of Excessive SomnolenceSleep Apnea SyndromesCross-Sectional StudiesFemaleHumansMalePrevalenceQuality of LifeSleepinessexcessive daytime sleepinessonlinequality of lifesleep apnea

Identifiers

PMID34170220
PMCPMC8726384
OpenAlexW3173917324

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.