Evidence map›Paper›PMID 34170090›Full record

ArticleJournal of veterinary science2021

Identification of a mimotope of an infectious bronchitis virus S1 protein.

Jingming Zhou, Jianan Li, Yanghui Li, Hongliang Liu, Yanhua Qi, Aiping Wang

Open access · goldAbstract read
In one paragraph

Article in Journal of veterinary science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.1field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Jingming ZhouSchool of Life Sciences, Zhengzhou University, Zhengzhou 450001, China.ORCID https://orcid.org/0000-0003-2079-1420
Jianan LiSchool of Life Sciences, Zhengzhou University, Zhengzhou 450001, China.ORCID https://orcid.org/0000-0002-0532-0412
Yanghui LiSchool of Life Sciences, Zhengzhou University, Zhengzhou 450001, China.ORCID https://orcid.org/0000-0003-4804-8049
Hongliang LiuSchool of Life Sciences, Zhengzhou University, Zhengzhou 450001, China.ORCID https://orcid.org/0000-0002-7533-6874
Yanhua QiSchool of Life Sciences, Zhengzhou University, Zhengzhou 450001, China.ORCID https://orcid.org/0000-0002-8796-3226
Aiping WangSchool of Life Sciences, Zhengzhou University, Zhengzhou 450001, China. pingaw@126.com.ORCID https://orcid.org/0000-0003-1661-8174
Zhengzhou University · CN

Funding

National Key Research and Development Program of China 2016YFD0500800
6 · The paper itself

Abstract

The S1 protein of the infectious bronchitis virus (IBV) is a major structural protein that induces the production of the virus-neutralization antibodies. The monoclonal antibody against the IBV M41 S1 protein was used as a target for biopanning. After three rounds of biopanning, randomly selected phages bound to the monoclonal antibody. Sequence analysis showed that the dominant sequence was SFYDFEMQGFFI. Indirect competitive enzyme-linked immunosorbent assay showed that SFYDFEMQGFFI is a mimotope of the S1 protein that was predicted by PepSurf. The mimotope may provide information for further structural and functional analyses of the S1 protein.

Indexed as

Antibodies, MonoclonalBacteriophagesBioprospectingInfectious bronchitis virusViral Structural ProteinsAntibodies, MonoclonalViral Structural ProteinsIBVmimotopeS1 protein

Identifiers

PMID34170090
PMCPMC8318793
OpenAlexW3172418414

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.