Evidence map›Paper›PMID 34170087›Full record

ArticleJournal of veterinary science2021

Novel reassortant 2.3.4.4B H5N6 highly pathogenic avian influenza viruses circulating among wild, domestic birds in Xinjiang, Northwest China.

Qian Zhang, Xindi Mei, Cheng Zhang, Juan Li, Nana Chang, Dilihuma Aji, Weifeng Shi, Yuhai Bi, Zhenghai Ma

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of veterinary science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 8 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Qian Zhang *Xinjiang Key Laboratory of Biological Resources and Genetic Engineering, College of Life Science and Technology, Xinjiang University, Urumqi 830046, China.ORCID https://orcid.org/0000-0002-2858-4840
Xindi Mei *Xinjiang Key Laboratory of Biological Resources and Genetic Engineering, College of Life Science and Technology, Xinjiang University, Urumqi 830046, China.ORCID https://orcid.org/0000-0002-7825-2254
Cheng ZhangXinjiang Key Laboratory of Biological Resources and Genetic Engineering, College of Life Science and Technology, Xinjiang University, Urumqi 830046, China.ORCID https://orcid.org/0000-0002-4900-231X
Juan LiKey Laboratory of Etiology and Emerging infections Disease in Shandong First Medical University, Taian 271016, China.ORCID https://orcid.org/0000-0001-9628-4850
Nana ChangXinjiang Key Laboratory of Biological Resources and Genetic Engineering, College of Life Science and Technology, Xinjiang University, Urumqi 830046, China.ORCID https://orcid.org/0000-0003-4261-1187
Dilihuma AjiXinjiang Key Laboratory of Biological Resources and Genetic Engineering, College of Life Science and Technology, Xinjiang University, Urumqi 830046, China.ORCID https://orcid.org/0000-0001-6727-723X
Weifeng ShiKey Laboratory of Etiology and Emerging infections Disease in Shandong First Medical University, Taian 271016, China.ORCID https://orcid.org/0000-0002-8717-2942
Yuhai BiXinjiang Key Laboratory of Biological Resources and Genetic Engineering, College of Life Science and Technology, Xinjiang University, Urumqi 830046, China.ORCID https://orcid.org/0000-0002-5595-363X
Zhenghai MaXinjiang Key Laboratory of Biological Resources and Genetic Engineering, College of Life Science and Technology, Xinjiang University, Urumqi 830046, China. mzhxju@126.com.ORCID https://orcid.org/0000-0002-0930-7696
Xinjiang University · CNEarly Warning (United States) · USTaishan Medical University · CN

Funding

National Major Science and Technology Projects of China 2018ZX10101004Xinjiang Uygur Autonomous Region Regional Cooperative Innovation Project 2017E01022
6 · The paper itself

Abstract

backgroundThe H5 avian influenza viruses (AIVs) of clade 2.3.4.4 circulate in wild and domestic birds worldwide. In 2017, nine strains of H5N6 AIVs were isolated from aquatic poultry in Xinjiang, Northwest China.

objectivesThis study aimed to analyze the origin, reassortment, and mutations of the AIV isolates.

methodsAIVs were isolated from oropharyngeal and cloacal swabs of poultry. Identification was accomplished by inoculating isolates into embryonated chicken eggs and performing hemagglutination tests and reverse transcription polymerase chain reaction (RT-PCR). The viral genomes were amplified with RT-PCR and then sequenced. The sequence alignment, phylogenetic, and molecular characteristic analyses were performed by using bioinformatic software.

resultsNine isolates originated from the same ancestor. The viral

conclusionsThese results suggest that the Northern Tianshan Mountain wetlands in Xinjiang may have a key role in AIVs disseminating from Central China to the Eurasian continent and East African.

Indexed as

AnimalsAnimals, DomesticAnimals, WildBirdsChinaInfluenza A virusInfluenza in BirdsPhylogenyReassortant VirusesVirulenceWhole Genome SequencingH5N6Highly pathogenic avian influenza viruspoultryreassortantwild bird

Identifiers

PMID34170087
PMCPMC8318794
OpenAlexW3160857298

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.