ArticleJournal of experimental zoology. Part B, Molecular and developmental evolution2021
The vitellogenin genes in Cynops orientalis: New insights on the evolution of the vtg gene family in amphibians.
Article in Journal of experimental zoology. Part B, Molecular and developmental evolution, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- A bioinformatic approach to characterize the vitellogenin receptor and the low density lipoprotein receptor superfamily in the newt Cynops orientalis.Scientific reports · 2025Article
- Egg Yolk Protein Homologs Identified in Live-Bearing Sharks: Co-Opted in the Lecithotrophy-to-Matrotrophy Shift?Genome biology and evolution · 2023Article
- The vitellogenin genes in Cynops orientalis: New insights on the evolution of the vtg gene family in amphibians.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The vitellogenins (Vtgs) are glycolipophosphoproteins that play a key role in constituting nutritional reserves for embryo development in nonmammalian vertebrates. However, additional functional roles have been evidenced. These vtg genes are present in multiple copies, different in number and sequences in various vertebrate lineages. The comprehension of the vtg gene family evolutionary history remains a matter of intense interrogation for this field of research. In tetrapods, information about vtg genes are limited to few taxa. Up to date concerning amphibians, detailed studies have been conducted only in Anura. Therefore, in this study, to further increase knowledge about vtg genes in Amphibia class, the urodele Cynops orientalis (Amphibia: Caudata) was analyzed and four complete vtg sequences were obtained. Moreover, genomic data available for the caecilians Microcaecilia unicolor and Rhinatrema bivittatum (Amphibia: Gymnophiona) were also included. In these amphibians, our findings evidenced the presence of a vtgI sequence ortholog to that of tetrapods, absent in Anura. Moreover, microsyntenic, phylogenetic, and gene conversion analyses allowed postulating two hypotheses to explain the complex evolutionary history of this gene family.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.