Evidence map›Paper›PMID 34169681›Full record

ArticleThe world journal of men's health2022

Seasonal Variations in Sex Steroids in a Young Male Population and Their Relationship with Plasma Levels of Vitamin D.

Pablo René Costanzo, Sebastián Matías Suárez, Andrea Elina Kozak, Pablo Knoblovits

Open access · diamondAbstract read
In one paragraph

Article in The world journal of men's health, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Pablo René CostanzoDepartment of Endocrinology, Metabolism and Nuclear Medicine, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina. pablo.costanzo@hospitalitaliano.org.ar.ORCID http://orcid.org/0000-0002-6130-2155
Sebastián Matías SuárezDepartment of Endocrinology, Metabolism and Nuclear Medicine, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.ORCID http://orcid.org/0000-0002-2038-9573
Andrea Elina KozakDepartment of Endocrinology, Metabolism and Nuclear Medicine, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.ORCID http://orcid.org/0000-0001-5268-2320
Pablo KnoblovitsDepartment of Endocrinology, Metabolism and Nuclear Medicine, Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.ORCID http://orcid.org/0000-0001-8939-922X
Hospital Italiano de Buenos Aires · AR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeVitamin D (VD) acts on sperm motility, capacitation and survival but its role in steroidogenesis is less clear. Aims: To analyze seasonal variations in sex steroids and VD in a healthy male population. MATERIALS AND

methodsTwenty-nine healthy males, 34.0±4.8 years were included. Blood collection in winter (W) and summer (S) was performed to measure: 25OHD, total testosterone (TT), free testosterone (FT), estradiol (E2), luteinizing hormone (LH), and sex hormone binding globulin (SHBG). Testosterone/estradiol (T/E2) ratio was calculated.

resultsIn W, lower levels of 25OHD: 18.8±7.2 ng/mL

conclusionsIn healthy young male population, seasonal variations were observed in 25OHD and LH levels (higher in S) and in TT, FT, SHBG levels, and T/E2 (higher in W). Lower values of TT and FT in S are accompanied by higher levels of LH, which rules out a central mechanism for lowering testosterone. 25OHD negatively correlated with TT, FT, and T/E2 and positively correlated with E2, suggesting a relationship between VD status and changes in gonadal steroids.

Indexed as

Seasonal variationsSex hormonesTestosteroneVitamin D

Identifiers

PMID34169681
PMCPMC8987141
OpenAlexW3172316200

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.