Evidence map›Paper›PMID 34169645›Full record

ArticleOrthodontics & craniofacial research2021

Automated landmarking for palatal shape analysis using geometric deep learning.

Balder Croquet, Harold Matthews, Jules Mertens, Yi Fan, Nele Nauwelaers, Soha Mahdi, Hanne Hoskens, Ahmed El Sergani, Tianmin Xu, Dirk Vandermeulen and 4 more

Open access · greenAbstract read
In one paragraph

Article in Orthodontics & craniofacial research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 12 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 6 countries.

Balder CroquetMedical Imaging Research Center, UZ Leuven, Leuven, Belgium.ORCID https://orcid.org/0000-0002-9539-5193
Harold MatthewsMedical Imaging Research Center, UZ Leuven, Leuven, Belgium.ORCID https://orcid.org/0000-0002-0524-0025
Jules MertensMedical Imaging Research Center, UZ Leuven, Leuven, Belgium.
Yi FanFacial Science Research Group, Murdoch Children's Research Institute, Parkville, Australia.
Nele NauwelaersMedical Imaging Research Center, UZ Leuven, Leuven, Belgium.
Soha MahdiMedical Imaging Research Center, UZ Leuven, Leuven, Belgium.
Hanne HoskensMedical Imaging Research Center, UZ Leuven, Leuven, Belgium.
Ahmed El SerganiCenter for Craniofacial and Dental Genetics, Department of Oral and Craniofacial Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID https://orcid.org/0000-0002-7680-932X
Tianmin XuDepartment of Orthodontics, Peking University School and Hospital of Stomatology, Beijing, China.
Dirk VandermeulenMedical Imaging Research Center, UZ Leuven, Leuven, Belgium.
Michael BronsteinDepartment of Computing, Imperial College London, London, UK.
Mary MarazitaDepartment of Oral and Craniofacial Sciences, Center for Craniofacial and Dental Genetics, Department of Human Genetics University of Pittsburgh, Pittsburgh, Pennsylvania, USA.
Seth WeinbergCenter for Craniofacial and Dental Genetics, Department of Oral and Craniofacial Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.ORCID https://orcid.org/0000-0001-9467-4556
Peter ClaesMedical Imaging Research Center, UZ Leuven, Leuven, Belgium.ORCID https://orcid.org/0000-0001-9489-9819
Universitair Ziekenhuis Leuven · BEUniversity of Pittsburgh · USPeking University · CNImperial College London · GB

Funding

Extending the Phenotype of Nonsyndromic Orofacial CleftsR01DE016148 · NIDCR · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI MARAZITA, MARY L., WEINBERG, SETH M · 2004 to 2018
$19.7M
KU Leuven BOF-C1KU Leuven C14/15/081KU Leuven C14/20/081National Institute of Health, National Institute for Dental & Craniofacial Research R01-DE016148NIDCR NIH HHS R01 DE016148Research Program of the Research Foundation Flanders (Belgium) G078518NResearch Program of the Research Foundation Flanders (Belgium) ISB0121N
6 · The paper itself

Abstract

objectivesTo develop and evaluate a geometric deep-learning network to automatically place seven palatal landmarks on digitized maxillary dental casts. SETTINGS AND SAMPLE POPULATION: The sample comprised individuals with permanent dentition of various ethnicities. The network was trained from manual landmark annotations on 732 dental casts and evaluated on 104 dental casts. MATERIALS AND

methodsA geometric deep-learning network was developed to hierarchically learn features from point-clouds representing the 3D surface of each cast. These features predict the locations of seven palatal landmarks.

resultsRepeat-measurement reliability was <0.3 mm for all landmarks on all casts. Accuracy is promising. The proportion of test subjects with errors less than 2 mm was between 0.93 and 0.68, depending on the landmark. Unusually shaped and large palates generate the highest errors. There was no evidence for a difference in mean palatal shape estimated from manual compared to the automatic landmarking. The automatic landmarking reduces sample variation around the mean and reduces measurements of palatal size.

conclusionsThe automatic landmarking method shows excellent repeatability and promising accuracy, which can streamline patient assessment and research studies. However, landmark indications should be subject to visual quality control.

Indexed as

Deep LearningHumansImaging, Three-DimensionalMaxillaPalateReproducibility of Results3D shape analysisautomatic landmarkinggeometric deep learningpalate

Identifiers

PMID34169645
PMCPMC8818261
OpenAlexW3176038182

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.