ArticleJournal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology2022
Article in Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
16 citing papers in PubMed, 23 citations in OpenAlex.
- Review
- Diagnosis and Management of Patients With Suspected Left-Sided Prosthetic Valve Endocarditis According to Cardiac FDG-PET CT Results.Open forum infectious diseases · 2026Article
- Article
- Current Management of Infective Endocarditis: A Narrative Review Focused on Unmet Clinical Needs and the Multidisciplinary Approach.Journal of cardiovascular development and disease · 2026Review
- Diagnostic value and interpretability of [EJNMMI research · 2026Article
- Multimodality Imaging in Infective Endocarditis: A Clinical Approach to Diagnosis.Medicina (Kaunas, Lithuania) · 2025Review
- New semiquantitative parameters in digital [EJNMMI reports · 2025Article
- Using machine learning to improve the diagnostic accuracy of the modified Duke/ESC 2015 criteria in patients with suspected prosthetic valve endocarditis - a proof of concept study.European journal of nuclear medicine and molecular imaging · 2024Article
- Dual-Time-Point 18F-FDG PET/CT in Infective Endocarditis: Impact of Delayed Imaging in the Definitive Diagnosis of Endocarditis.Biomedicines · 2024Article
- The Role of theJournal of personalized medicine · 2024Article
- Fluorine-18-Fluorodeoxyglucose PET/CT Proved Valvular Endocarditis in a Native Valve Patient.Cureus · 2023Article
- Patients with Artificial Heart Valves.Deutsches Arzteblatt international · 2023Review
- Review of cardiovascular imaging in the Journal of Nuclear Cardiology 2022: positron emission tomography, computed tomography, and magnetic resonance.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2023Review
- FDG PET in infective endocarditis: There are still horizons to conquer.Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology · 2022Article
- Risk Factors Associated with Poor Outcome in Patients with Infective Endocarditis: An Italian Single-Center Experience.Infectious disease reports · 2022Article
- Multimodality Imaging in the Diagnosis of Prosthetic Valve Endocarditis: A Brief Review.Frontiers in cardiovascular medicine · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundInternational guidance recognizes the shortcomings of the modified Duke Criteria (mDC) in diagnosing infective endocarditis (IE) when transoesophageal echocardiography (TOE) is equivocal.
methodsDual-center retrospective study (2010-2018) of patients undergoing myocardial suppression PET for NVE and PVE. Cases were classified by mDC pre- and post-PET, and evaluated against discharge diagnosis. Receiver Operating Characteristic (ROC) analysis and net reclassification index (NRI) assessed diagnostic performance. Valve standardized uptake value (SUV) was recorded.
results69/88 PET studies were evaluated across 668 patients. At discharge, 20/32 had confirmed NVE, 22/37 PVE, and 19/69 patients required surgery. PET accurately re-classified patients from possible, to definite or rejected (NRI: NVE 0.89; PVE 0.90), with significant incremental benefit in both NVE (AUC 0.883 vs 0.750) and PVE (0.877 vs 0.633). Sensitivity and specificity were 75% and 92% in NVE; 87% and 86% in PVE. Duration of antibiotics and C-reactive Protein level did not impact performance. No diagnostic SUV cut-off was identified.
conclusionPET improves diagnostic certainty when combined with mDC in NVE and PVE.
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.