Evidence map›Paper›PMID 34169398›Full record

ArticleAnnals of biomedical engineering2021

On the Periodicity of Cardiovascular Fluid Dynamics Simulations.

Martin R Pfaller, Jonathan Pham, Nathan M Wilson, David W Parker, Alison L Marsden

Abstract read
In one paragraph

Article in Annals of biomedical engineering, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Patient-specificFrontiers in cardiovascular medicine · 2024
    Review
  14. Cloud Computing to Enable Wearable-Driven Longitudinal Hemodynamic Maps.International Conference for High Performance Computing, Networking, Storage and Analysis : [proceedings]. SC (Conference : Supercomputing) · 2023
    Article
  15. Review
  16. Article
  17. Review
  18. Article
  19. A Brief Note on Building Augmented Reality Models for Scientific Visualization.Finite elements in analysis and design : the international journal of applied finite elements and computer aided engineering · 2023
    Article
  20. Automated generation of 0D and 1D reduced-order models of patient-specific blood flow.International journal for numerical methods in biomedical engineering · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Martin R PfallerDepartment of Pediatrics (Cardiology), Institute for Computational and Mathematical Engineering, Bioengineering, Stanford University, Stanford, USA. pfaller@stanford.edu.ORCID http://orcid.org/0000-0001-5760-2617
Jonathan PhamDepartment of Mechanical Engineering, Stanford University, Stanford, USA.
Nathan M WilsonOpen Source Medical Software Corporation, Santa Monica, USA.
David W ParkerStanford Research Computing, Stanford University, Stanford, USA.
Alison L MarsdenDepartment of Pediatrics (Cardiology), Institute for Computational and Mathematical Engineering, Bioengineering, Stanford University, Stanford, USA.

Funding

Enabling reliable cardiovascular simulations via uncertainty quantificationR01EB018302 · NIBIB · STANFORD UNIVERSITY · PI MARSDEN, ALISON L · 2016 to 2019
$1.7M
SCH: INT: A Virtual Surgery Simulator to Accelerate Medical Training in Cardiovascular Disease R01EB029362 · NIBIB · STANFORD UNIVERSITY · PI MARSDEN, ALISON L · 2019 to 2022
$1.4M
Automated data curation to ensure model credibility in the Vascular Model RepositoryR01LM013120 · NLM · STANFORD UNIVERSITY · PI MARSDEN, ALISON L · 2019 to 2021
$1.0M
NIBIB NIH HHS R01 EB018302NIBIB NIH HHS R01 EB029362NIBIB NIH HHS R01EB029362NLM NIH HHS R01 LM013120U.S. National Library of Medicine R01LM013120
6 · The paper itself

Abstract

Three-dimensional cardiovascular fluid dynamics simulations typically require computation of several cardiac cycles before they reach a periodic solution, rendering them computationally expensive. Furthermore, there is currently no standardized method to determine whether a simulation has yet reached that periodic state. In this work, we propose the use of an asymptotic error measurement to quantify the difference between simulation results and their ideal periodic state using open-loop lumped-parameter modeling. We further show that initial conditions are crucial in reducing computational time and develop an automated framework to generate appropriate initial conditions from a one-dimensional model of blood flow. We demonstrate the performance of our initialization method using six patient-specific models from the Vascular Model Repository. In our examples, our initialization protocol achieves periodic convergence within one or two cardiac cycles, leading to a significant reduction in computational cost compared to standard methods. All computational tools used in this work are implemented in the open-source software platform SimVascular. Automatically generated initial conditions have the potential to significantly reduce computation time in cardiovascular fluid dynamics simulations.

Indexed as

Cardiovascular Physiological PhenomenaHemodynamicsHydrodynamicsModels, CardiovascularBlood Flow VelocityHumansPeriodicitySoftware0D modeling1D modelingBoundary conditionsCardiovascular fluid dynamicsInitial conditionsLumped-parameter networksPatient-specific modelingReduced-order modelingRepository

Identifiers

PMID34169398
PMCPMC9831274

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.