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ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2021

Factors related to specialized palliative care use and aggressive care at end of life in Japanese patients with advanced solid cancers: a cohort study.

Yusuke Hiratsuka, Takayuki Oishi, Mitsunori Miyashita, Tatsuya Morita, Jennifer W Mack, Yuko Sato, Masahiro Takahashi, Keigo Komine, Ken Saijo, Chikashi Ishioka and 1 more

Abstract read
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In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Associations between perceived interpersonal support and aggressiveness of care in the last month of life among patients with advanced cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Article
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Yusuke HiratsukaDepartment of Palliative Medicine, Takeda General Hospital, Aizu Wakamatsu, Japan.
Takayuki OishiDepartment of Clinical Oncology, Tohoku University School of Medicine, Sendai, Japan.
Mitsunori MiyashitaDepartment of Palliative Nursing, Tohoku University School of Medicine, 2-1 Seiryo-machi, Aoba-ku, Sendai, 980-8575, Japan. miya@med.tohoku.ac.jp.ORCID http://orcid.org/0000-0002-7637-0409
Tatsuya MoritaDepartment of Palliative and Supportive Care, Palliative Care Team, and Seirei Hospice, Seirei Mikatahara General Hospital, Hamamatsu, Japan.
Jennifer W MackDepartment of Pediatric Oncology and Center for Population Sciences, Dana-Farber Cancer Institute, Boston, MA, USA.
Yuko SatoDepartment of Clinical Oncology, Tohoku University School of Medicine, Sendai, Japan.
Masahiro TakahashiDepartment of Clinical Oncology, Tohoku University School of Medicine, Sendai, Japan.
Keigo KomineDepartment of Medical Oncology, Tohoku University Hospital, Sendai, Japan.
Ken SaijoDepartment of Clinical Oncology, Tohoku University School of Medicine, Sendai, Japan.
Chikashi IshiokaDepartment of Clinical Oncology, Tohoku University School of Medicine, Sendai, Japan.
Akira InoueDepartment of Palliative Medicine, Tohoku University School of Medicine, Sendai, Japan.

Funding

Tohoku University 15K15161Tohoku University 18K10266
6 · The paper itself

Abstract

purposeThis study aimed to (1) describe characteristics of aggressive care at the end of life (EOL) and (2) identify factors associated with specialized palliative care use (SPC) and aggressive care at the EOL among Japanese patients with advanced cancer.

methodsThis single-center, follow-up cohort study involved patients with advanced cancer who received chemotherapy at Tohoku University Hospital. Patients were surveyed at enrollment, and we followed clinical events for 5 years from enrollment in the study. We performed multivariate logistic regression analysis to identify independent factors related to SPC use and chemotherapy in the last month before death.

resultsWe analyzed a total of 135 patients enrolled between January 2015 and January 2016. No patients were admitted to the intensive care unit, and few received resuscitation or ventilation. We identified no factors significantly associated with SPC use. Meanwhile, younger age (20-59 years, odds ratio [OR] 4.10; 95% confidence interval [CI] 1.30-12.91; p = 0.02) and no receipt of SPC (OR 4.32; 95% CI 1.07-17.37; p = 0.04) were associated with chemotherapy in the last month before death.

conclusionYounger age and a lack of SPC were associated with chemotherapy at the EOL in patients with advanced cancer in Japan. These findings suggest that Japanese patients with advanced cancer may benefit from access to SPC.

Indexed as

NeoplasmsTerminal CareAdultCohort StudiesDeathFollow-Up StudiesHumansJapanMiddle AgedPalliative CareRetrospective StudiesYoung AdultAdvanced cancerAggressive careChemotherapyEnd-of-lifePerception

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.