Evidence map›Paper›PMID 34169327›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2021

Personality matters: relationship between personality characteristics, spirituality, demoralization, and perceived quality of life in a sample of end-of-life cancer patients.

Ada Ghiggia, Vanni Pierotti, Valentina Tesio, Andrea Bovero

Open access · hybridAbstract read
In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
4.2field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 43 citations in OpenAlex.

  1. Pooled it
  2. Demoralization and spirituality in oncology: an integrative systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Characteristics and influencing factors of demoralization in ovarian cancer: a latent profile analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Observational
  7. Article
  8. Article
  9. Body compassion as a mediator between demoralization, fear of cancer recurrence, and body image concerns in women with breast cancer.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Article
  10. Article
  11. Article
  12. Demoralization: A concept analysis through a scoping review methodology.International journal of nursing studies advances · 2025
    Article
  13. Article
  14. The mediating effect of positive coping in the association between inner strength and demoralization in lung cancer chemotherapy patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  15. Demoralization in breast cancer survivors.Frontiers in psychology · 2025
    Article
  16. Review
  17. Article
  18. Article
  19. Status and influential factors of spiritual well-being in cancer patients with drug clinical trials: a cross-sectional study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2023
    Article
  20. Demoralization profiles and their association with depression and quality of life in Chinese patients with cancer: a latent class analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Ada GhiggiaClinical Psychology Unit, AOU Città dela Salute e della Scienza, Corso Bramante 88, 10126, Turin, Italy. ada.ghiggia@unito.it.ORCID http://orcid.org/0000-0003-1347-9762
Vanni PierottiClinical Psychology Unit, AOU Città dela Salute e della Scienza, Corso Bramante 88, 10126, Turin, Italy.
Valentina TesioDepartment of Psychology, University of Turin, Via Verdi 10, 10124, Turin, Italy.
Andrea BoveroClinical Psychology Unit, AOU Città dela Salute e della Scienza, Corso Bramante 88, 10126, Turin, Italy.
Azienda Ospedaliera Citta' della Salute e della Scienza di Torino · ITUniversity of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposePersonality could be an interesting dimension to explore in end-of-life cancer patients, in order to investigate how personality affects quality of life. Thus, this study aimed to investigate the relationship among personality through the Big Five Inventory (BFI), spirituality, and demoralization and to explore their impact on their quality of life.

methodsA sample of 210 end-of-life Italian cancer patients were assessed with the BFI, the Demoralization Scale (DS), the Functional Assessment of Chronic Illness Therapy-Spiritual Well-Being (FACIT-SP-12), the Functional Assessment of Cancer Therapy Scale-General Measure (FACT-G), and the Karnofsky performance status.

resultsCorrelational analysis highlighted a significantly negative relationship between extraversion and agreeableness traits and all the demoralization dimensions. On the other side, neuroticism trait was significantly and positively correlated with the Demoralization Scale (p < 0.01). To understand the impact of these variables on quality of life (FACT-G), we performed a hierarchical multiple regression: in the final model, demoralization remained the strongest contributing factor (β =  - 0.509, p < 0.001), followed by neuroticism (β =  - 0.175, p < 0.001), spirituality (β = 0.163, p = 0.015), and Karnofsky index (β = 0.115, p = 0.012).

conclusionOur data underlined how both the neuroticism trait and demoralization are correlated with a worst health status in terminal cancer patients, whereas spirituality is a protective factor. The study of personality may allow to better understand the inner patient's experience and improve communication between patient and healthcare staff in order to build and apply better-tailored psychological treatment.

Indexed as

DemoralizationNeoplasmsDeathHumansPersonalityQuality of LifeSpiritualityCancerDemoralizationEnd-of-lifeHealth-related quality of lifePersonality

Identifiers

PMID34169327
PMCPMC8550274
OpenAlexW3176405459

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.