Evidence map›Paper›PMID 34169257›Full record

ArticleCJC open2021

Liver Congestion Assessed by Hepatic Vein Waveforms in Patients With Heart Failure.

Yukiko Sugawara, Akiomi Yoshihisa, Shinji Ishibashi, Mitsuko Matsuda, Yukio Yamadera, Himika Ohara, Yasuhiro Ichijo, Koichiro Watanabe, Yu Hotsuki, Fumiya Anzai and 10 more

Open access · goldAbstract read
In one paragraph

Article in CJC open, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
  3. Imaging of Congestion in Cardio-renal Syndrome.Current heart failure reports · 2025
    Review
  4. Review
  5. Review
  6. Observational
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 1 institution in 1 country.

Yukiko SugawaraDepartment of Cardiovascular Medicine Fukushima Medical University Hospital, Fukushima, Japan.
Akiomi YoshihisaDepartment of Cardiovascular Medicine Fukushima Medical University Hospital, Fukushima, Japan.
Shinji IshibashiDepartment of Clinical Laboratory Medicine, Fukushima Medical University Hospital, Fukushima, Japan.
Mitsuko MatsudaDepartment of Clinical Laboratory Medicine, Fukushima Medical University Hospital, Fukushima, Japan.
Yukio YamaderaDepartment of Clinical Laboratory Medicine, Fukushima Medical University Hospital, Fukushima, Japan.
Himika OharaDepartment of Cardiovascular Medicine Fukushima Medical University Hospital, Fukushima, Japan.
Yasuhiro IchijoDepartment of Cardiovascular Medicine Fukushima Medical University Hospital, Fukushima, Japan.
Koichiro WatanabeDepartment of Cardiovascular Medicine Fukushima Medical University Hospital, Fukushima, Japan.
Yu HotsukiDepartment of Cardiovascular Medicine Fukushima Medical University Hospital, Fukushima, Japan.
Fumiya AnzaiDepartment of Cardiovascular Medicine Fukushima Medical University Hospital, Fukushima, Japan.
Yu SatoDepartment of Cardiovascular Medicine Fukushima Medical University Hospital, Fukushima, Japan.
Yusuke KimishimaDepartment of Cardiovascular Medicine Fukushima Medical University Hospital, Fukushima, Japan.
Tetsuro YokokawaDepartment of Cardiovascular Medicine Fukushima Medical University Hospital, Fukushima, Japan.
Tomofumi MisakaDepartment of Cardiovascular Medicine Fukushima Medical University Hospital, Fukushima, Japan.
Shinya YamadaDepartment of Cardiovascular Medicine Fukushima Medical University Hospital, Fukushima, Japan.
Takamasa SatoDepartment of Cardiovascular Medicine Fukushima Medical University Hospital, Fukushima, Japan.
Takashi KaneshiroDepartment of Cardiovascular Medicine Fukushima Medical University Hospital, Fukushima, Japan.
Masayoshi OikawaDepartment of Cardiovascular Medicine Fukushima Medical University Hospital, Fukushima, Japan.
Atsushi KobayashiDepartment of Cardiovascular Medicine Fukushima Medical University Hospital, Fukushima, Japan.
Yasuchika TakeishiDepartment of Cardiovascular Medicine Fukushima Medical University Hospital, Fukushima, Japan.
Fukushima Medical University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt has been reported that the pattern of hepatic vein (HV) waveforms determined by abdominal ultrasonography is useful for the diagnosis of hepatic fibrosis in patients with chronic liver disease. We aim to clarify the clinical implications of HV waveform patterns in patients with heart failure (HF).

methodsWe measured HV waveforms in 350 HF patients, who were then classified into 3 categories based on their waveforms: those with a continuous pattern (C group); those whose V wave ran under the baseline (U group), and those with a reversed V wave (R group). We performed right-heart catheterization, and examined the rate of postdischarge cardiac events, such as cardiac death and rehospitalization due to worsening HF.

resultsThe number of patients in each of the 3 HV waveform groups was as follows: C group, n = 158; U group, n = 152, and R group, n = 40. The levels of B-type natriuretic peptide (R vs C and U; 245.8 vs 111.7 and 216.6 pg/mL;

conclusionAmong HF patients, those with reversed V waves had higher right atrial pressure and were at higher risk of adverse prognosis.

Identifiers

PMID34169257
PMCPMC8209365
OpenAlexW3128199778

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.