Evidence map›Paper›PMID 34169195›Full record

ArticleKidney international reports2021

A Cost-Effective Analysis of the CYCLE-HD Randomized Controlled Trial.

Daniel S March, Adam W Hurt, Charlotte E Grantham, Darren R Churchward, Hannah M L Young, Patrick J Highton, Maurice Dungey, Nicolette C Bishop, Alice C Smith, Matthew P M Graham-Brown and 2 more

Open access · goldAbstract read
In one paragraph

Article in Kidney international reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. Article
  6. Article
  7. Observational
  8. Review
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Daniel S MarchDepartment of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom.
Adam W HurtDepartment of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom.
Charlotte E GranthamDepartment of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom.
Darren R ChurchwardDepartment of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom.
Hannah M L YoungUniversity Hospitals of Leicester NHS Trust, Leicester, United Kingdom.
Patrick J HightonSchool of Sport, Exercise and Health Sciences, Loughborough University, Loughborough, United Kingdom.
Maurice DungeyDepartment of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom.
Nicolette C BishopNational Institute of Health Research Leicester Biomedical Research Center, Leicester, United Kingdom.
Alice C SmithDepartment of Health Sciences, University of Leicester, United Kingdom.
Matthew P M Graham-BrownDepartment of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom.
Nicola J CooperDepartment of Health Sciences, University of Leicester, United Kingdom.
James O BurtonDepartment of Cardiovascular Sciences, University of Leicester, Leicester, United Kingdom.
University of Leicester · GBNIHR Leicester Biomedical Research Centre · GBUniversity Hospitals of Leicester NHS Trust · GBLoughborough University · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionNo formal cost-effectiveness analysis has been performed for programs of cycling exercise during dialysis (intradialytic cycling [IDC]). The objective of this analysis is to determine the effect of a 6-month program of IDC on health care costs.

methodsThis is a retrospective formal cost-effectiveness analysis of adult participants with end-stage kidney disease undertaking in-center maintenance hemodialysis enrolled in the CYCLE-HD trial. Data on hospital utilization, primary care consultations, and prescribed medications were extracted from medical records for the 6 months before, during, and after a 6-month program of thrice-weekly IDC. The cost-effectiveness analysis was conducted from a health care service perspective and included the cost of implementing the IDC intervention. The base-case analyses included a 6-month "within trial" analysis and a 12-month "within and posttrial" analysis considering health care utilization and quality of life (QoL) outcomes.

resultsData from the base-case within trial analysis, based on 109 participants (

conclusionA 6-month program of IDC is cost-effective and the implementation of these programs nationally should be a priority.

Indexed as

cost-effectivenessexercisehemodialysisintradialytic exerciserehabilitation

Identifiers

PMID34169195
PMCPMC8207470
OpenAlexW3145734670

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.