Evidence map›Paper›PMID 34169149›Full record

ArticleNeurology. Genetics2021

Adult-Onset Spinal Muscular Atrophy due to Mutations in the

Angela Sung, Paolo Moretti, Aziz Shaibani

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neurology. Genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. NovelNeurology. Genetics · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Angela SungDepartment of Neurology (A. Sung), University of California San Diego; Department of Neurology (P.M.), University of Utah Health Science Center; George E. Wahlen VA Medical Center (P.M.), Salt Lake City, UT; and Nerve and Muscle Center of Texas (A. Shaibani), Houston.
Paolo MorettiDepartment of Neurology (A. Sung), University of California San Diego; Department of Neurology (P.M.), University of Utah Health Science Center; George E. Wahlen VA Medical Center (P.M.), Salt Lake City, UT; and Nerve and Muscle Center of Texas (A. Shaibani), Houston.
Aziz ShaibaniDepartment of Neurology (A. Sung), University of California San Diego; Department of Neurology (P.M.), University of Utah Health Science Center; George E. Wahlen VA Medical Center (P.M.), Salt Lake City, UT; and Nerve and Muscle Center of Texas (A. Shaibani), Houston.
University of California, San Diego · USUniversity of Utah · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo expand our knowledge of the range of clinical phenotypes associated with vaccinia-related kinase 1 (

methodsWe present clinical and molecular data of 2 individuals with slowly progressive weakness and a clinical syndrome consistent with adult-onset spinal muscular atrophy without pontocerebellar atrophy.

resultsGenetic testing revealed likely pathogenic variants in the

conclusionsWe report 2 cases with

Identifiers

PMID34169149
PMCPMC8220962
OpenAlexW3175832324

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.