Evidence map›Paper›PMID 34168977›Full record

ArticleFrontiers in oncology2021

Cardia Gastric Cancer Is Associated With Increased PIK3CA Amplifications and HER2 Expression Than Noncardia Gastric Cancer According to Lauren Classification.

Shih-Min Pai, Kuo-Hung Huang, Ming-Huang Chen, Wen-Liang Fang, Yee Chao, Su-Shun Lo, Anna Fen-Yau Li, Chew-Wun Wu, Yi-Ming Shyr

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 3 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Shih-Min PaiDivision of General Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan.
Kuo-Hung HuangDivision of General Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan.
Ming-Huang ChenSchool of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Wen-Liang FangDivision of General Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan.
Yee ChaoSchool of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Su-Shun LoSchool of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Anna Fen-Yau LiSchool of Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan.
Chew-Wun WuDivision of General Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan.
Yi-Ming ShyrDivision of General Surgery, Department of Surgery, Taipei Veterans General Hospital, Taipei, Taiwan.
National Yang Ming Chiao Tung University · TWTaipei Veterans General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo date, few reports have investigated genetic alterations and clinicopathological features in cardia and noncardia gastric cancer (GC).

methodsIn total, 435 GC patients receiving curative surgery were included. The clinicopathological features, recurrence patterns, prognoses and genetic alterations were compared between cardia and noncardia GC patients.

resultsAmong the 435 enrolled patients, 47 (10.8%) had cardia GC. Compared with noncardia GC, cardia GC was associated with more intestinal-type tumors and similar initial recurrence patterns and 5-year overall survival (OS; 50.8% vs. 50.5%,

conclusionsCardia GC is not an independent prognostic factor. In cardia GC patients with intestinal-type GC,

Indexed as

cardiagastric cancergenetic alterationHER2 expressionnoncardiaPIK3CA amplification

Identifiers

PMID34168977
PMCPMC8217656
OpenAlexW3168070009

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.