Evidence map›Paper›PMID 34168656›Full record

ArticleFrontiers in immunology2021

The cGAS/STING-TBK1-IRF Regulatory Axis Orchestrates a Primitive Interferon-Like Antiviral Mechanism in Oyster.

Xue Qiao, Yanan Zong, Zhaoqun Liu, Zhaojun Wu, Yuanmei Li, Lingling Wang, Linsheng Song

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 39 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Xue QiaoLiaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian, China.
Yanan ZongLiaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian, China.
Zhaoqun LiuLiaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian, China.
Zhaojun WuLiaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian, China.
Yuanmei LiLiaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian, China.
Lingling WangLiaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian, China.
Linsheng SongLiaoning Key Laboratory of Marine Animal Immunology, Dalian Ocean University, Dalian, China.
Qingdao National Laboratory for Marine Science and Technology · CNDalian Ocean University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Interferon (IFN) system is considered as the first defense line against viral infection, and it has been extensively studied in vertebrates from fish to mammals. In invertebrates, Vagos from arthropod and IFN-like protein (

Indexed as

ImmunityAnimalsCrassostreaDNA VirusesHost-Pathogen InteractionsInterferon Regulatory FactorsMembrane ProteinsNucleotidyltransferasesPoly I-CProtein Serine-Threonine KinasesSignal TransductionInterferon Regulatory FactorsMembrane ProteinsNucleotidyltransferasesPoly I-CProtein Serine-Threonine Kinasesantiviral immunityCrassostrea gigascyclic GMP-AMP (cGAMP) synthase (cGAS)interferon-like systemstimulator of interferon genes (STING)

Identifiers

PMID34168656
PMCPMC8218723
OpenAlexW3172814365

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.