Evidence map›Paper›PMID 34168641›Full record

ArticleFrontiers in immunology2021

Neutrophil Extracellular Traps Activate Proinflammatory Functions of Human Neutrophils.

Daniel Dömer, Tabea Walther, Sonja Möller, Martina Behnen, Tamás Laskay

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 150 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
150citing papers in PubMed, 1 pooled it
10.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

150 citing papers in PubMed, 1 synthesis or guideline pooled it, 201 citations in OpenAlex.

  1. Pooled it
  2. Prime Editing for p47The New England journal of medicine · 2026
    Trial
  3. Article
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  5. Review
  6. Review
  7. Review
  8. Article
  9. Dynamics of Extracellular Traps in Vaginal Dysbiosis Associated withInternational journal of molecular sciences · 2026
    Article
  10. Heat-KilledInternational journal of molecular sciences · 2026
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Review
  20. Review

90 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Daniel DömerDepartment of Infectious Diseases and Microbiology, University of Lübeck, Lübeck, Germany.
Tabea WaltherDepartment of Infectious Diseases and Microbiology, University of Lübeck, Lübeck, Germany.
Sonja MöllerDepartment of Infectious Diseases and Microbiology, University of Lübeck, Lübeck, Germany.
Martina BehnenDepartment of Infectious Diseases and Microbiology, University of Lübeck, Lübeck, Germany.
Tamás LaskayDepartment of Infectious Diseases and Microbiology, University of Lübeck, Lübeck, Germany.
University of Lübeck · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neutrophil extracellular traps (NETs) consist of decondensed nuclear chromatin that is associated with proteins and are released by neutrophils during an inflammatory response. Released NETs are able to capture pathogens, prevent their dissemination and potentially kill them

Indexed as

B-Cell Activating FactorCells, CulturedExtracellular TrapsHumansImmunity, InnateInflammationInflammation MediatorsInterleukin-8MAP Kinase Signaling SystemNADPH Oxidase 2Neutrophil ActivationNeutrophilsPhagocytosisProto-Oncogene Proteins c-aktReactive Oxygen SpeciesB-Cell Activating FactorCYBB protein, humanInflammation MediatorsInterleukin-8NADPH Oxidase 2Proto-Oncogene Proteins c-aktReactive Oxygen SpeciesTNFSF13B protein, humanBAFFeffector functionsinflammationNET formationneutrophil extracellular trapsneutrophilsROS production

Identifiers

PMID34168641
PMCPMC8217666
OpenAlexW3172916279

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.