Evidence map›Paper›PMID 34168569›Full record

ArticleFrontiers in physiology2021

Localized Oxygen Exchange Platform for Intravital Video Microscopy Investigations of Microvascular Oxygen Regulation.

Richard J Sové, Stephanie Milkovich, Hristo N Nikolov, David W Holdsworth, Christopher G Ellis, Graham M Fraser

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in physiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

Richard J SovéDepartment of Biomedical Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, United States.
Stephanie MilkovichDepartment of Medical Biophysics, University of Western Ontario, London, ON, Canada.
Hristo N NikolovRobarts Research Institute, University of Western Ontario, London, ON, Canada.
David W HoldsworthDepartment of Medical Biophysics, University of Western Ontario, London, ON, Canada.
Christopher G EllisDepartment of Medical Biophysics, University of Western Ontario, London, ON, Canada.
Graham M FraserDivision of BioMedical Sciences, Faculty of Medicine, Memorial University of Newfoundland, St. John's, NL, Canada.
Western University · CAJohns Hopkins Medicine · USMemorial University of Newfoundland · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intravital microscopy has proven to be a powerful tool for studying microvascular physiology. In this study, we propose a gas exchange system compatible with intravital microscopy that can be used to impose gas perturbations to small localized regions in skeletal muscles or other tissues that can be imaged using conventional inverted microscopes. We demonstrated the effectiveness of this system by locally manipulating oxygen concentrations in rat

Indexed as

blood flowcapillarymathematical modelingmicrocirculationmicrofluidicsoxygen saturationoxygen transport

Identifiers

PMID34168569
PMCPMC8217830
OpenAlexW3172327471

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.