Evidence map›Paper›PMID 34168476›Full record

ReviewDiabetes, metabolic syndrome and obesity : targets and therapy2021

The Association Between Obesity and Social Isolation as Well as Loneliness in the Adult Population: A Systematic Review.

André Hajek, Benedikt Kretzler, Hans-Helmut König

Abstract readReview
In one paragraph

Review in Diabetes, metabolic syndrome and obesity : targets and therapy, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Biopsychosocial and Environmental Factors That Impact Brain-Gut-Microbiome Interactions in Obesity.Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association · 2026
    Pooled it
  2. Pollution, stress response, and obesity: A systematic review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Training Healthcare Professionals to Deliver a Group-Based Intervention for People Living With Severe Obesity: Lessons From the PROGROUP Feasibility Trial.Journal of human nutrition and dietetics : the official journal of the British Dietetic Association · 2026
    Trial
  6. Observational
  7. Mobile Internet Use and Obesity Among Chinese Adults.Journal of prevention (2022) · 2026
    Article
  8. Review
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  16. [The relationship between obesity, social isolation, and mental health-results from the LIFE adult study].Bundesgesundheitsblatt, Gesundheitsforschung, Gesundheitsschutz · 2024
    Article
  17. Article
  18. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

André HajekDepartment of Health Economics and Health Services Research, University Medical Center Hamburg-Eppendorf, Hamburg, 20246, Germany.ORCID 0000-0002-6886-2745
Benedikt KretzlerDepartment of Health Economics and Health Services Research, University Medical Center Hamburg-Eppendorf, Hamburg, 20246, Germany.
Hans-Helmut KönigDepartment of Health Economics and Health Services Research, University Medical Center Hamburg-Eppendorf, Hamburg, 20246, Germany.ORCID 0000-0001-5711-6862

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeObesity is associated with adverse health outcomes and can result in feelings of loneliness or social isolation, for example due to stigmatization. These factors are in turn associated with morbidity and mortality. Thus far, a systematic review is lacking with regard to the association between obesity, social isolation and loneliness. Therefore, our aim was to fill this gap in knowledge. MATERIALS AND

methodsThree established electronic databases (PubMed, PsycInfo, as well as CINAHL) were searched. Observational studies examining the link between obesity and loneliness or social isolation were included. Disease-specific samples were excluded.

resultsIn sum, six studies have been included. While some studies point to an association between obesity and increased loneliness levels, it should be acknowledged that findings are mixed. Study quality was quite high.

conclusionThis systematic review showed that the literature is inconclusive and incomplete. Further research is required to shed further light on these associations. Moreover, studies from countries outside Europe, based on longitudinal data and using objective assessments of obesity, are urgently required. Gender differences should be further explored.

Indexed as

excess weightlonelinessobesityoverweightsocial exclusionsocial isolation

Identifiers

PMID34168476
PMCPMC8216698

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.