ArticleInfection and drug resistance2021
Species Diversity and Antifungal Susceptibilities of Oral Yeasts from Patients with Head and Neck Cancer.
Article in Infection and drug resistance, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 11 citations in OpenAlex.
- Clinical factors associated with fluconazole resistance in oral Candida from xerostomic head and neck cancer patients.Odontology · 2026Article
- Does the use of topical azoles have an impact on antifungal resistance?The Journal of antimicrobial chemotherapy · 2025Article
- Oral Microbiota and Inflammatory Bowel Diseases: Detection of Emerging Fungal Pathogens and Herpesvirus.Biomedicines · 2025Article
- Prevalence, drug resistance and genetic diversity ofMycology · 2025Article
- Review
- Oral mycobiota and pancreatic ductal adenocarcinoma.BMC cancer · 2022Article
- Distribution and antifungal susceptibility pattern ofVirulence · 2022Review
- Prevalence and Antifungal Susceptibility Profile of OralMedicina (Kaunas, Lithuania) · 2022Article
- Extensive Diversity and Prevalent Fluconazole Resistance among Environmental Yeasts from Tropical China.Genes · 2022Article
- Comparison of the antifungal effect of voriconazole and fluconazole on oral candidiasis before and during radiotherapy.Dental research journal · 2022Article
- Spectrum and management of rareTherapeutic advances in infectious diseaseReview
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Authors and funding
9 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeTo investigate the colonization and susceptibility to antifungal drugs of oral yeasts in head and neck cancer patients in Hainan, China.
methodsOral mucosa samples from 211 head and neck cancer patients were collected. Oral yeasts were isolated and identified to species by rDNA ITS sequencing. The susceptibilities of all yeasts to amphotericin B, fluconazole, fluorocytosine, itraconazole, and ketoconazole were determined.
resultsYeasts were isolated from 124 of the 211 oral swabs. The 124 yeast isolates were classified into following 10 species, from the most frequent to the least frequent,
conclusionGiven the high prevalence of oral yeast colonization in head and neck cancer patients and the observed resistance of certain yeast isolates to the five antifungal drugs, our results suggest that rapid identification and susceptibility testing should be implemented before antifungal treatment is applied among patients with head and neck cancer in Hainan.
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