Evidence map›Paper›PMID 34168459›Full record

ArticleJournal of multidisciplinary healthcare2021

Survival Time and Associated Factors Among Adults Living with HIV After Initiation of HAART in South Gondar, Northwest Ethiopia: A Retrospective Cohort.

Genzeb Deres, Zelalem Mehari Nigussie, Muluken Genetu Chanie, Nigusu Worku

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Article in Journal of multidisciplinary healthcare, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
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10citing papers in PubMed, 1 pooled it
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Genzeb DeresBlood Bank, Debre-Tabor Branch, Amhara National Regional State, Ethiopia.
Zelalem Mehari NigussieSchool of Public Health, Bahir Dar University, Bahir Dar, Ethiopia.ORCID 0000-0003-1015-7047
Muluken Genetu ChanieDepartment of Health Systems and Policy, School of Public Health, College of Medicine and Health Sciences, Wollo University, Dessie, Ethiopia.ORCID 0000-0001-7059-1449
Nigusu WorkuDepartment of Health Systems and Policy, University of Gondar, Gondar, Ethiopia.ORCID 0000-0001-7262-286X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAntiretroviral therapy consistently improves the survival of people living with HIV and contributes to preventing the development of new infections. Studies of antiretroviral therapy programs in Africa have shown a high mortality rate during the first 6 months after initiation of HAART in rural health facilities. This study looks at survival time and associated factors among adults with HIV in south Gondar, Northwest Ethiopia.

methodsA 5-year retrospective cohort study design was conducted using patient records among 746 adults living with HIV/AIDS. A systematic random sampling technique was used to select respondents after proportional allocation was made for all health facilities included in the study. Epi-info version 7 and STATA 12 were used for data entry and analysis, respectively. Kaplan-Meier survival analysis was used to estimate mean survival time and a life table was used to estimate survival probability after initiation of HAART.

resultsA total of 746 respondents were followed for a median of 60 months. There were 102 (13.67%) deaths yielding an overall mortality rate of 2.59/1,000-person year observation (95% CI=0.02136-0.031736). Age of respondents >43 years (AHR=2.790; 95% CI=1.495-5.206), bedridden (AHR=9.57; 95% CI=3.87-23.64), past TB treatment (AHR=0.86; 95% CI=0.46-0.609), baseline WHO stage IV (AHR=3.02; 95% CI=1.77-5.18), pneumonia after ART start (AHR=3.6; 95% CI=1.4-9.2), INH prophylaxis (AHR=2.58; 95% CI=1.232-5.188), ambulatory functional status (AHR=5.86; 95% CI=2.67-12.86), and disclosure status (AHR=0.423; 95% CI=0.261-0.685) were significant predictors for survival time after initiation of HAART among adults living with HIV.

conclusionThe mortality rate was highly (13.67%) observed in the early phase of antiretroviral treatment. Being ambulatory and bedridden, age of respondents >43 years, past TB treatment, baseline WHO stage IV, pneumonia after HAART, INH prophylaxis, and disclosure status were independent predictors of mortality.

Indexed as

adultsHAARTsouth Gondarsurvival time

Identifiers

PMID34168459
PMCPMC8217907

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.