Evidence map›Paper›PMID 34168456›Full record

ArticleNeuropsychiatric disease and treatment2021

A Clinical Observation of Intravenous Thrombolysis in Acute Ischemic Stroke with Minor Trauma.

Yansen Cui, Liquan Wang

Open access · goldAbstract read
In one paragraph

Article in Neuropsychiatric disease and treatment, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 2 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Yansen CuiDepartment of Emergency, Linyi People's Hospital, Linyi, 276001, People's Republic of China.
Liquan WangDepartment of Emergency, Linyi People's Hospital, Linyi, 276001, People's Republic of China.
Linyi People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study aimed to observe the curative effect of intravenous thrombolysis with alteplase in patients with acute ischemic stroke and minor trauma.

methodsThe data of 25 patients with minor trauma who were treated in our department from January to December 2018 were analyzed retrospectively (observation group), and during the same period, 25 thrombolytic patients were enrolled as the control group. Brain computed tomography (CT) was performed before and at three days after thrombolysis. NIHSS scores were recorded before thrombolysis and at one, three, and seven days after thrombolysis. Additionally, bleeding rate after thrombolysis and 90-day mRS scores were recorded.

resultsThe differences in 1-day, 3-day, and 7-day NIHSS scores and 90-day mRS scores between the two groups were not statistically significant (P>0.05). The bleeding rate was higher in the observation group than in the control group, and this was statistically significant (P<0.05).

conclusionIntravenous thrombolysis with alteplase has a good curative effect in acute ischemic stroke patients with minor trauma. The bleeding rate was significantly higher than in the control group, but there was no significant difference in the long-term curative effect.

Indexed as

acute ischemic strokealteplaseintravenous thrombolysisthe curative effect and safety

Identifiers

PMID34168456
PMCPMC8216721
OpenAlexW3167036917

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.