Evidence map›Paper›PMID 34168425›Full record

ArticleClinical ophthalmology (Auckland, N.Z.)2021

Role of Cold Balanced Salt Solution (BSS) in the Prophylaxis of Cystoid Macular Edema After Cataract Surgery: A Prospective Randomized Study.

Alessandro Meduri, Giovanni William Oliverio, Loredana Bergandi, Gabriella De Salvo, Rino Frisina, Cosimo Mazzotta, Pasquale Aragona

Open access · goldAbstract read
In one paragraph

Article in Clinical ophthalmology (Auckland, N.Z.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Alessandro MeduriBiomedical, Dental and Morphological and Functional Images Sciences Department, University of Messina, Messina, Italy.ORCID 0000-0001-7546-9178
Giovanni William OliverioBiomedical, Dental and Morphological and Functional Images Sciences Department, University of Messina, Messina, Italy.ORCID 0000-0003-3127-9756
Loredana BergandiDepartment of Oncology, University of Torino, Turin, Italy.ORCID 0000-0003-0951-7340
Gabriella De SalvoEye Unit, University Hospital Southampton Foundation Trust, Southampton, UK.ORCID 0000-0002-1185-6942
Rino FrisinaDepartment of Neurosciences - Ophthalmology, University of Padova, Padua, Italy.ORCID 0000-0002-0247-2680
Cosimo MazzottaDepartmental Ophthalmology Unit, Alta Val d'Elsa Hospital, Siena, Italy.ORCID 0000-0002-1829-9288
Pasquale AragonaBiomedical, Dental and Morphological and Functional Images Sciences Department, University of Messina, Messina, Italy.ORCID 0000-0002-9582-9799
University of Messina · ITUniversity Hospital Southampton NHS Foundation Trust · GBUniversity of Padua · ITUniversity of Turin · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the postoperative effect on central retinal macular thickness of a cooled irrigating eye solution used during cataract surgery. PATIENTS AND

methodsIn this prospective, single-center study, 100 eyes of 50 patients (26 males and 24 females) were evaluated with spectral domain optical coherence tomography (SD-OCT) before and after phacoemulsification for senile cataract. Eyes were randomly divided into two groups based on the irrigating solution used during surgery: Group 1, 50 eyes received intraoperative irrigating solution at room temperature (~20.0±0.1°C); and Group 2, 50 fellow eyes received cold intraoperative irrigating solution (2.7±0.1°C). Changes in central macular thickness (CMT) were evaluated in both groups by SD-OCT macular raster scan for the nine Early Treatment of Diabetic Retinopathy Study (ETDRS) subfields and total macular volume, performed pre-surgery, and 1 and 4 weeks post-surgery.

resultsDespite there being no significant differences in variables between the two groups preoperatively, significant increases in CMT were observed at 1 week after surgery in both groups (

conclusionThe use of a cooled irrigating eye solution during phacoemulsification may be beneficial in preventing the possible development of postoperative macular thickening. Further clinical studies may support this finding.

Indexed as

cataract surgerycentral macular thicknesscold intraoperative irrigating solutioncystoid macular edemaphacoemulsificationspectral domain optical coherence tomography

Identifiers

PMID34168425
PMCPMC8216722
OpenAlexW3176971374

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.