Evidence map›Paper›PMID 34168401›Full record

ReviewWorld journal of gastroenterology2021

Mucosal lesions of the upper gastrointestinal tract in patients with ulcerative colitis: A review.

Yan Sun, Zhe Zhang, Chang-Qing Zheng, Li-Xuan Sang

Registry-linked trialOpen access · hybridAbstract readReview
In one paragraph

Review in World journal of gastroenterology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06092593 (Evaluation of Upper Gastrointestinal Tract Lesions in Ulcerative Colitis Patients in Assiut University), which is not on this map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
8.3field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06092593 unknown statusnot on this mapstarted 2024, after this paper: background citation

Evaluation of Upper Gastrointestinal Tract Lesions in Ulcerative Colitis Patients in Assiut University

TypeobservationalSponsorAssiut UniversityRan2024 to 2025Enrolled70ConditionsUpper Gastrointestinal DisorderArmsUpper endoscopy
3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it, 76 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. Regulatory Role of IGF2BP2 in Intestinal Mucosal Barrier Dysfunction in Ulcerative Colitis.The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology · 2025
    Article
  16. Article
  17. Article
  18. Frontiers in microbiology · 2025
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Yan SunDepartment of Gastroenterology, Shengjing Hospital of China Medical University, Shenyang 110022, Liaoning Province, China.
Zhe ZhangDepartment of Gastroenterology, Shengjing Hospital of China Medical University, Shenyang 110022, Liaoning Province, China.
Chang-Qing ZhengDepartment of Gastroenterology, Shengjing Hospital of China Medical University, Shenyang 110022, Liaoning Province, China.
Li-Xuan SangDepartment of Gastroenterology, Shengjing Hospital of China Medical University, Shenyang 110022, Liaoning Province, China. sanglixuan2008@163.com.
China Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ulcerative colitis (UC) is a chronic, nonspecific, relapsing inflammatory bowel disease. The colorectum is considered the chief target organ of UC, whereas upper gastrointestinal (UGI) tract manifestations are infrequent. Recently, emerging evidence has suggested that UC presents complications in esophageal, stomachic, and duodenal mucosal injuries. However, UC-related UGI tract manifestations are varied and frequently silenced or concealed. Moreover, the endoscopic and microscopic characteristics of UGI tract complicated with UC are nonspecific. Therefore, UGI involvement may be ignored by many clinicians. In addition, no standard criteria have been established for patients with UC who should undergo fibrogastroduodenoscopy. Furthermore, specific treatment recommendations may be needed for patients with UC-associated UGI lesions. Herein, we review the esophageal, gastric, and duodenal mucosal lesions of the UC-associated UGI tract, as well as the potential pathogenesis and therapy.

Indexed as

Colitis, UlcerativeInflammatory Bowel DiseasesUpper Gastrointestinal TractDuodenumHumansStomachEndoscopic and microscopic manifestationsInflammatory bowel diseaseUlcerative colitisUpper gastrointestinal tract

Identifiers

PMID34168401
PMCPMC8192286
OpenAlexW3168995815

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.