ReviewJournal of applied mechanics2021
Magnetic Forces Enable Control of Biological Processes In Vivo.
Review in Journal of applied mechanics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed, 3 citations in OpenAlex.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
Similar to mechanical forces that can induce profound biological effects, magnetic fields can have a broad range of implications to biological systems, from magnetoreception that allows an organism to detect a magnetic field to perceive direction, altitude, or location, to the use of heating induced by magnetic field for altering neuron activity. This review focuses on the application of magnetic forces generated by magnetic iron oxide nanoparticles (MIONs), which can also provide imaging contrast and mechanical/thermal energy in response to an external magnetic field, a special feature that distinguishes MIONs from other nanomaterials. The magnetic properties of MIONs offer unique opportunities for enabling control of biological processes under different magnetic fields. Here, we describe the approaches of utilizing the forces generated by MIONs under an applied magnetic field to control biological processes and functions, including the targeting of drug molecules to a specific tissue, increasing the vessel permeability for improving drug delivery, and activating a particular viral vector for spatial control of genome editing in vivo. The opportunities of using nanomagnets for a broad range of biomedical applications are briefly discussed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.