ArticleNature chemistry2021
Chemical-mediated translocation in protocell-based microactuators.
Article in Nature chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
22 citing papers in PubMed.
- Signal-induced recruitment and dispatchment in reconfigurable phase-separated protocell networks.Nature chemistry · 2026Article
- Prototissues: Assembly strategies, collective behaviors, and emerging applications.Bioactive materials · 2026Review
- Coacervate Vesicles as Adaptive Platforms for Synthetic Biology and Smart Materials.Chemistry (Weinheim an der Bergstrasse, Germany) · 2025Review
- Interfacial assembly of biomimetic MOF-based porous membranes on coacervates to build complex protocells and prototissues.Nature chemistry · 2025Article
- Spatio-Temporal Processes of Diffusion-Controlled Communication in Hierarchical Multi-Compartments.Angewandte Chemie (International ed. in English) · 2025Article
- Cytomimetic calcification in chemically self-regulated prototissues.Nature communications · 2025Article
- Programmed Fabrication of Vesicle-Based Prototissue Fibers with Modular Functionalities.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Wetware network-based AI: a chemical approach to embodied cognition for robotics and artificial intelligence.Frontiers in robotics and AI · 2025Article
- Artificial-goosebump-driven microactuation.Nature materials · 2024Article
- Exploring Emergent Properties in Enzymatic Reaction Networks: Design and Control of Dynamic Functional Systems.Chemical reviews · 2024Review
- Superstructural ordering in self-sorting coacervate-based protocell networks.Nature chemistry · 2024Article
- Regulation of species metabolism in synthetic community systems by environmental pH oscillations.Nature communications · 2023Article
- Dual enzyme-powered chemotactic cross β amyloid based functional nanomotors.Nature communications · 2023Article
- Biomimetic behaviors in hydrogel artificial cells through embedded organelles.Proceedings of the National Academy of Sciences of the United States of America · 2023Article
- Engineering Tissue-Scale Properties with Synthetic Cells: Forging One from Many.ACS synthetic biology · 2023Review
- Autonomic Integration in Nested Protocell Communities.Journal of the American Chemical Society · 2023Article
- Non-interfacial self-assembly of synthetic protocells.Biomaterials research · 2023Article
- Assembly of Fillable Microrobotic Systems by Microfluidic Loading with Dip Sealing.Advanced materials (Deerfield Beach, Fla.) · 2023Article
- Photoswitchable gating of non-equilibrium enzymatic feedback in chemically communicating polymersome nanoreactors.Nature chemistry · 2023Article
- Signal processing and generation of bioactive nitric oxide in a model prototissue.Nature communications · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Artificial cell-like communities participate in diverse modes of chemical interaction but exhibit minimal interfacing with their local environment. Here we develop an interactive microsystem based on the immobilization of a population of enzyme-active semipermeable proteinosomes within a helical hydrogel filament to implement signal-induced movement. We attach large single-polynucleotide/peptide microcapsules at one or both ends of the helical protocell filament to produce free-standing soft microactuators that sense and process chemical signals to perform mechanical work. Different modes of translocation are achieved by synergistic or antagonistic enzyme reactions located within the helical connector or inside the attached microcapsule loads. Mounting the microactuators on a ratchet-like surface produces a directional push-pull movement. Our methodology opens up a route to protocell-based chemical systems capable of utilizing mechanical work and provides a step towards the engineering of soft microscale objects with increased levels of operational autonomy.
Indexed as
Identifiers
34168327What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.