ArticleScientific reports2021
Alterations in gut microbiota linked to provenance, sex, and chronic wasting disease in white-tailed deer (Odocoileus virginianus).
Article in Scientific reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
17 citing papers in PubMed, 28 citations in OpenAlex.
- Maternal chronic wasting disease infection restricts fetal head size in white-tailed deer (Prion · 2026Article
- Microbiome and resistome of the European bison (Bison bonasus).Scientific reports · 2026Article
- Identifying candidate gut microbiota indicators for Alzheimer's disease through integrated data.mSystems · 2026Article
- Distinct Rumen Microbial Features and Host Metabolic Responses in Three Cervid Species.Animals : an open access journal from MDPI · 2025Article
- Article
- Are you my mother? When host genetics and gut microbiota tell different phylogenetic stories in the Africanized honey bee hybrid (Microbiology spectrum · 2025Article
- Variations in Intestinal Microbiota Among Three Species in the Cervidae Family Under the Same Feeding Conditions.Veterinary sciences · 2025Article
- Metagenomic analysis of the faecal microbiota and AMR in roe deer in Western Pomerania.Scientific reports · 2025Article
- Comparison of Fecal Microbiota and Metabolites Between Captive and Grazing Male Reindeer.Animals : an open access journal from MDPI · 2024Article
- High-Energy Supplemental Feeding Shifts Gut Microbiota Composition and Function in Red Deer (Animals : an open access journal from MDPI · 2024Article
- Prospective fecal microbiomic biomarkers for chronic wasting disease.Microbiology spectrum · 2024Article
- Analysis of the Intestinal and Faecal Bacterial Microbiota of the Cervidae Family UsingMicroorganisms · 2023Review
- Environmental factors and gut microbiota: Toward better conservation of deer species.Frontiers in microbiology · 2023Review
- Article
- Captivity Shifts Gut Microbiota Communities in White-Lipped Deer (Animals : an open access journal from MDPI · 2022Article
- Seasonal variations in the composition and diversity of gut microbiota in white-lipped deer (PeerJ · 2022Article
- Possibilities and limits for using the gut microbiome to improve captive animal health.Animal microbiome · 2021Review
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
Abstract
Chronic wasting disease (CWD) is a fatal, contagious, neurodegenerative prion disease affecting both free-ranging and captive cervid species. CWD is spread via direct or indirect contact or oral ingestion of prions. In the gastrointestinal tract, prions enter the body through microfold cells (M-cells), and the abundance of these cells can be influenced by the gut microbiota. To explore potential links between the gut microbiota and CWD, we collected fecal samples from farmed and free-ranging white-tailed deer (Odocoileus virginianus) around the Midwest, USA. Farmed deer originated from farms that were depopulated due to CWD. Free-ranging deer were sampled during annual deer harvests. All farmed deer were tested for CWD via ELISA and IHC, and we used 16S rRNA gene sequencing to characterize the gut microbiota. We report significant differences in gut microbiota by provenance (Farm 1, Farm 2, Free-ranging), sex, and CWD status. CWD-positive deer from Farm 1 and 2 had increased abundances of Akkermansia, Lachnospireacea UCG-010, and RF39 taxa. Overall, differences by provenance and sex appear to be driven by diet, while differences by CWD status may be linked to CWD pathogenesis.
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Registered trials
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