ArticleNature communications2021
Diversity-oriented synthesis of nanographenes enabled by dearomative annulative π-extension.
Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
17 citing papers in PubMed.
- Diversity-Oriented Two-Step Annulative π-Extension Enables Access to Structurally Complex Nanographenes.Angewandte Chemie (International ed. in English) · 2026Article
- The advent of molecular nanocarbon biology.Chemical science · 2026Review
- Bottom-Up Approach for the Synthesis of Contorted Nanographenes by Cp*Co(III)-Catalyzed Annulative-π-Extension-Cyclization Cascade.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026Article
- π-Electron reorganization in polycyclic aromatic hydrocarbons toward BT.2020-compliant narrowband red emitters.National science review · 2026Article
- Article
- Synthesis of Chrysene-Based Nanographenes by a Successive APEX Reaction.Precision chemistry · 2025Article
- Birch reductive arylation by mechanochemical anionic activation of polycyclic aromatic compounds.Nature communications · 2025Article
- Functionalization and solubilization of polycyclic aromatic compounds by sulfoniumization.Chemical science · 2025Article
- Reimagining Dearomatization: Arenophile-Mediated Single-Atom Insertions and π-Extensions.Accounts of chemical research · 2025Article
- Arylboronic Acid Pinacol Esters as Stable Boron Sources for Dihydrodibenzoborepin Derivatives and a Dibenzoborole.Molecules (Basel, Switzerland) · 2024Article
- A Generalized Nomenclature Scheme for Graphene Pores, Flakes, and Edges, and an Algorithm for Their Generation and Numbering.Nanomaterials (Basel, Switzerland) · 2023Article
- Microwave-assisted C-C bond formation of diarylacetylenes and aromatic hydrocarbons on carbon beads under continuous-flow conditions.Communications chemistry · 2023Article
- Electronic Control of the Scholl Reaction: Selective Synthesis of Spiro vs Helical Nanographenes.Angewandte Chemie (International ed. in English) · 2023Article
- π-Extended Rubrenes via Dearomative Annulative π-Extension Reaction.Journal of the American Chemical Society · 2023Article
- Acenaphthenoannulation Induced by the Dual Lewis Acidity of Alumina.Chemistry (Weinheim an der Bergstrasse, Germany) · 2022Article
- Rapid access to polycyclic N-heteroarenes from unactivated, simple azines via a base-promoted Minisci-type annulation.Nature communications · 2022Article
- Diels-Alder Cycloaddition with CO, COMaterials (Basel, Switzerland) · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Nanographenes and polycyclic aromatic hydrocarbons (PAHs) are among the most important classes of compounds, with potential applications in nearly all areas of science and technology. While the theoretically possible number of nanographene structures is extraordinary, most of these molecules remain synthetically out of reach due to a lack of programmable and diversity-oriented synthetic methods, and their potentially huge structure-property diversity has not been fully exploited. Herein we report a diversity-oriented, growth-from-template synthesis of nanographenes enabled by iterative annulative π-extension (APEX) reactions from small PAH starting materials. The developed dearomative annulative π-extension (DAPEX) reaction enables π-elongation at the less-reactive M-regions of PAHs, and is successfully combined with complementary APEX reactions that occur at K- and bay-regions to access a variety of previously untapped nanographenes.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.