ArticleNature communications2021
PGRL2 triggers degradation of PGR5 in the absence of PGRL1.
Article in Nature communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed, 66 citations in OpenAlex.
- Moderate overexpression of PROTON GRADIENT REGULATION 5 improves photosynthetic performance and plant growth under fluctuating low light in Arabidopsis thaliana.The Plant journal : for cell and molecular biology · 2026Article
- Harnessing natural variation for photosynthetic improvement in next-generation crop breeding.Journal of integrative plant biology · 2026Review
- The thioredoxin system protects PSI from photoinhibition in coordination with PSI cyclic electron transport under fluctuating light conditions.Plant & cell physiology · 2026Article
- Importance of cysteine residues in the C-terminal region of PGRL1 for PSI photoprotection in Chlamydomonas reinhardtii.Plant physiology · 2026Article
- Cyclic electron flow around photosystem I provides energy production and photoprotection in C4 plants.Plant physiology · 2026Article
- Donor- and Acceptor-Side Protection Against Photosystem I Photoinhibition inInternational journal of molecular sciences · 2025Article
- Review
- Additive Effects of Multiple Photoprotective Mechanisms Drive Efficient Photosynthesis Under Variable Light Conditions.Plant, cell & environment · 2025Article
- PROTON GRADIENT REGULATION 5 enables efficient C4 photosynthesis under fluctuating light.Plant physiology · 2025Article
- Structure, regulation and assembly of the photosynthetic electron transport chain.Nature reviews. Molecular cell biology · 2025Review
- Tethering ferredoxin-NADP+ reductase to photosystem I promotes photosynthetic cyclic electron transfer.The Plant cell · 2025Article
- Photosynthetic control at the cytochrome b6f complex.The Plant cell · 2024Review
- A pgr5 suppressor screen uncovers two distinct suppression mechanisms and links cytochrome b6f complex stability to PGR5.The Plant cell · 2024Article
- Strategies for adaptation to high light in plants.aBIOTECH · 2024Review
- Light-Driven HPlants (Basel, Switzerland) · 2024Review
- Regulation of Microalgal Photosynthetic Electron Transfer.Plants (Basel, Switzerland) · 2024Review
- Divergent Protein Redox Dynamics and Their Relationship with Electron Transport Efficiency during Photosynthesis Induction.Plant & cell physiology · 2024Article
- Adjustment of light-responsive NADP dynamics in chloroplasts by stromal pH.Nature communications · 2023Article
- Current Insights into the Redox Regulation Network in Plant Chloroplasts.Plant & cell physiology · 2023Review
- High cyclic electron transfer via the PGR5 pathway in the absence of photosynthetic control.Plant physiology · 2023Article
Corrections and comments
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Authors and funding
8 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In plants, inactivation of either of the thylakoid proteins PGR5 and PGRL1 impairs cyclic electron flow (CEF) around photosystem I. Because PGR5 is unstable in the absence of the redox-active PGRL1, but not vice versa, PGRL1 is thought to be essential for CEF. However, we show here that inactivation of PGRL2, a distant homolog of PGRL1, relieves the need for PGRL1 itself. Conversely, high levels of PGRL2 destabilize PGR5 even when PGRL1 is present. In the absence of both PGRL1 and PGRL2, PGR5 alters thylakoid electron flow and impairs plant growth. Consequently, PGR5 can operate in CEF on its own, and is the target of the CEF inhibitor antimycin A, but its activity must be modulated by PGRL1. We conclude that PGRL1 channels PGR5 activity, and that PGRL2 triggers the degradation of PGR5 when the latter cannot productively interact with PGRL1.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.