Evidence map›Paper›PMID 34168015›Full record

ArticleJournal of nuclear medicine : official publication, Society of Nuclear Medicine2022

Oliver Sartor, Christian la Fougère, Markus Essler, Samer Ezziddin, Gero Kramer, Jörg Ellinger, Luke Nordquist, John Sylvester, Giovanni Paganelli, Avivit Peer and 5 more

Erratum issuedOpen access · hybridAbstract read
In one paragraph

Article in Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
3.4field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 30 citations in OpenAlex.

  1. Review
  2. Article
  3. Combination prostate-specific membrane antigen-targeted radiopharmaceutical therapy in metastatic prostate cancer.The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of... · 2025
    Review
  4. Article
  5. Current oncology (Toronto, Ont.) · 2024
    Review
  6. Article
  7. Review
  8. Sequential and Combination Therapies ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
  9. Journal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
  10. Safety and Survival Outcomes ofJournal of nuclear medicine : official publication, Society of Nuclear Medicine · 2023
    Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Safety and Efficacy ofCancers · 2022
    Article
  16. AlphaBet: Combination of Radium-223 and [Frontiers in medicine · 2022
    Article
  17. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors at 13 institutions in 6 countries.

Oliver SartorTulane Cancer Center, Tulane University School of Medicine, New Orleans, Louisiana; osartor@tulane.edu.
Christian la FougèreDepartment of Nuclear Medicine and Clinical Molecular Imaging, University Hospital Tübingen, Tübingen, Germany.
Markus EsslerClinic and Polyclinic for Nuclear Medicine, University Hospital Bonn, Bonn, Germany.
Samer EzziddinDepartment of Nuclear Medicine, Saarland University, Homburg, Germany.
Gero KramerUrology Clinic, Medical University of Vienna, Vienna, Austria.
Jörg EllingerClinic for Urology and Pediatric Urology, University Hospital Bonn, Bonn, Germany.
Luke NordquistGuam Research Network LLC, Omaha, Nebraska.
John Sylvester21st Century Oncology-Sarasota, Lakewood Ranch, Florida.
Giovanni PaganelliScientific Institute of Romagna for the Study and Treatment of Tumors, UOC Nuclear Medicine, Meldola, Italy.
Avivit PeerRambam MC, Haifa, Israel.
Martin BögemannDepartment of Urology, University Hospital Münster, Münster, Germany.
Jeffrey MeltzerBayer HealthCare, Whippany, New Jersey.
Per SandströmBayer HealthCare, Whippany, New Jersey.
Frank VerholenBayer Consumer Care, Basel, Switzerland.
Daniel Y SongRadiation Oncology, Johns Hopkins University, Baltimore, Maryland.
Bayer (United States) · USUniversity Hospital Bonn · DE21st Century Oncology (United States) · USBayer (Switzerland) · CHIstituto Scientifico Romagnolo per lo Studio e la Cura dei Tumori · ITJohns Hopkins University · USMedical University of Vienna · ATRambam Health Care Campus · ILResearch Network (United States) · USSaarland University · DETulane University · USUniversity Children's Hospital Tübingen · DEUniversity Hospital Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We analyzed real-world clinical outcomes of sequential α-/β-emitter therapy for metastatic castration-resistant prostate cancer (mCRPC).

Indexed as

Prostate-Specific AntigenProstatic Neoplasms, Castration-ResistantClinical Studies as TopicDipeptidesHeterocyclic Compounds, 1-RingHumansLigandsLutetiumMaleProstateTreatment OutcomeDipeptidesHeterocyclic Compounds, 1-RingLigandsLutetiumProstate-Specific Antigen177Lu-prostate-specific membrane antigen223Rametastatic castration-resistant prostate cancerreal-world evidencetreatment sequence

Identifiers

PMID34168015
PMCPMC8978191
OpenAlexW3177104530

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.