Evidence map›Paper›PMID 34168008›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2021

The Rac-GAP alpha2-Chimaerin Signals via CRMP2 and Stathmins in the Development of the Ocular Motor System.

Luis Carretero-Rodriguez, Ragnheiður Guðjónsdóttir, Ivana Poparic, Madeline Louise Reilly, Mary Chol, Isaac H Bianco, Marco Chiapello, Renata Feret, Michael J Deery, Sarah Guthrie

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. GlialeLife · 2026
    Article
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  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Luis Carretero-RodriguezSchool of Life Sciences, University of Sussex, Brighton BN7 9QG, United Kingdom.
Ragnheiður GuðjónsdóttirSchool of Life Sciences, University of Sussex, Brighton BN7 9QG, United Kingdom.
Ivana PoparicDepartment of Developmental Neurobiology, King's College London, London SE1 1UL, United Kingdom.
Madeline Louise ReillySchool of Life Sciences, University of Sussex, Brighton BN7 9QG, United Kingdom.
Mary CholDepartment of Developmental Neurobiology, King's College London, London SE1 1UL, United Kingdom.
Isaac H BiancoDepartment of Neuroscience, Physiology and Pharmacology, University College London, London WC1E 6BT, United Kingdom.ORCID https://orcid.org/0000-0002-3149-4862
Marco ChiapelloCambridge Centre for Proteomics, Cambridge Systems Biology Centre, Department of Biochemistry, University of Cambridge, Cambridge CB2 1QR, United Kingdom.
Renata FeretInstitute for Sustainable Plant Protection, National Research Council, 10135 Torino, Italy.ORCID https://orcid.org/0000-0002-9719-4459
Michael J DeeryInstitute for Sustainable Plant Protection, National Research Council, 10135 Torino, Italy.
Sarah GuthrieSchool of Life Sciences, University of Sussex, Brighton BN7 9QG, United Kingdom s.guthrie@sussex.ac.uk.
University of Sussex · GBInstitute for Sustainable Plant Protection · ITKing's College London · GBUniversity College London · GBUniversity of Cambridge · GB

Funding

Medical Research Council MR/L020742/1
6 · The paper itself

Abstract

A precise sequence of axon guidance events is required for the development of the ocular motor system. Three cranial nerves grow toward, and connect with, six extraocular muscles in a stereotyped pattern, to control eye movements. The signaling protein alpha2-chimaerin (α2-CHN) plays a pivotal role in the formation of the ocular motor system; mutations in

Indexed as

AnimalsAxon GuidanceChimerin 1Duane Retraction SyndromeEye MovementsMotor NeuronsNerve Tissue ProteinsOculomotor MusclesSignal TransductionStathminZebrafishZebrafish ProteinsChimerin 1dpysl2b protein, zebrafishNerve Tissue ProteinsStathminZebrafish Proteinsalpha2-chimaerinchimaerinCRMP2ocular motor systemstathmin

Identifiers

PMID34168008
PMCPMC8336708
OpenAlexW3175822313

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.