Evidence map›Paper›PMID 34167722›Full record

ArticleThe Journal of investigative dermatology2021

Western Diet and Psoriatic-Like Skin and Joint Diseases: A Potential Role for the Gut Microbiota.

Renuka R Nayak

Open access · bronzeAbstract readComment
In one paragraph

Article in The Journal of investigative dermatology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 13 citations in OpenAlex.

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  8. Frontiers in medicine · 2023
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author at 1 institution in 1 country.

Renuka R NayakDivision of Rheumatology, Department of Medicine, University of California San Francisco, San Francisco, California, USA. Electronic address: Renuka.Nayak@ucsf.edu.
University of California, San Francisco · US

Funding

The impact of the gut microbiome on rheumatoid arthritis treatmentK08AR073930 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI NAYAK, RENUKA RAJENDRA · 2018 to 2022
$981k
NIAMS NIH HHS K08 AR073930
6 · The paper itself

Abstract

Shi et al. (2021) in "Short-term Western diet intake promotes IL-23-mediated skin and joint inflammation accompanied by changes to the gut microbiota in mice" show that Western diet (WD) exacerbates an IL-23 minicircle‒mediated model of psoriasis and psoriatic arthritis, with an expansion of IL-17A‒expressing γδ T cells and shifts to the gut microbial community. WD-associated inflammation is mitigated by diet manipulation or antibiotic administration. These results suggest that dietary manipulation may be useful in the treatment of IL-23‒mediated disease, possibly through the modulation of the gut microbiota.

Indexed as

Gastrointestinal MicrobiomeJoint DiseasesPsoriasisAnimalsDiet, WesternMiceSkin

Identifiers

PMID34167722
PMCPMC11225535
OpenAlexW3174461074

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.