Evidence map›Paper›PMID 34167526›Full record

ArticleCardiovascular ultrasound2021

Afterload-related reference values for myocardial work indices.

Qiancheng Li, Hui Wang, Haiyan Feng, Tingfan Wu, Ying Yang, Dongmei Gao, Lina Sun

Open access · goldAbstract read
In one paragraph

Article in Cardiovascular ultrasound, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
1.4field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Qiancheng Li *Department of CT, Jilin Province FAW General Hospital, Changchun, China.
Hui Wang *Department of Ultrasound, China-Japan Union Hospital of Jilin University, Changchun, China.
Haiyan FengDepartment of Ultrasound, China-Japan Union Hospital of Jilin University, Changchun, China.
Tingfan WuGE Healthcare, Clinical Education Team(CET), Pudong New Town, Shanghai, China.
Ying YangDepartment of Ultrasound, China-Japan Union Hospital of Jilin University, Changchun, China.
Dongmei GaoDepartment of Ultrasound, China-Japan Union Hospital of Jilin University, Changchun, China.
Lina SunDepartment of Ultrasound, China-Japan Union Hospital of Jilin University, Changchun, China. sunlina@jlu.edu.cn.
Jilin University · CNJilin Province Tumor Hospital · CNUnion Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe novel noninvasive pressure-strain loop (PSL) is a reliable tool that reflects myocardial work (MW). Systolic blood pressure (SBP) is the only independent factor for MW indices. However, afterload-related reference values have not been previously reported. The aim of the present study was to establish reference values for MW parameters by wide range SBP grading.

methodsWe prospectively selected healthy individuals and subjects with SBP ≥ 140 mmHg at the time of study without myocardial remodeling. MW parameters were collected and the reference values achieved were grouped by SBP in 10-mmHg.

resultsSignificant differences were noted among the SBP-groups for global work index (GWI) and global constructive work (GCW). The majority of statistical comparisons of the differences in GWI and GCW were significant at each SBP-group. With SBP ranging from 90 to 189 mmHg, the parameters GWI and GCW tended to increase linearly with afterload. Overall, the global wasted work (GWW) tended to rise as SBP was increased, but not all of the differences noted in GWW were significant for each SBP-group. Global work efficiency (GWE) remained stable across all SBP-groups, with the exception of a slight drop noted when it exceeded 160 mmHg.

conclusionsThe amount of MW but not the work efficiency varied greatly according to the different afterload. This finding cannot be ignored during clinical research or diagnosis and afterload-related reference values are required to make a reasonable judgment on the myocardial function.

Indexed as

EchocardiographyVentricular Function, LeftBlood PressureHumansMyocardiumReference ValuesStroke VolumeAfterloadMyocardial workReference values

Identifiers

PMID34167526
PMCPMC8228927
OpenAlexW3138455270

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.