Evidence map›Paper›PMID 34167467›Full record

ArticleBMC neurology2021

Impact of the COVID-19 pandemic and post-epidemic periods on the process of endovascular treatment for acute anterior circulation ischaemic stroke.

Tangqin Zhang, Chu Chen, Xiangjun Xu, Junfeng Xu, Ke Yang, Youqing Xu, Lili Yuan, Qian Yang, Xianjun Huang, Zhiming Zhou

Abstract read
In one paragraph

Article in BMC neurology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. COVID-19 and stroke in women: impact on clinical, psychosocial and research aspects.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2024
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Tangqin Zhang *Department of Neurology, Yijishan Hospital, Wannan Medical College, 2# Zheshan West Road, Wuhu, 241001, Anhui Province, China.
Chu Chen *Department of Neurology, Yijishan Hospital, Wannan Medical College, 2# Zheshan West Road, Wuhu, 241001, Anhui Province, China.
Xiangjun Xu *Department of Neurology, Yijishan Hospital, Wannan Medical College, 2# Zheshan West Road, Wuhu, 241001, Anhui Province, China.
Junfeng XuDepartment of Neurology, Yijishan Hospital, Wannan Medical College, 2# Zheshan West Road, Wuhu, 241001, Anhui Province, China.
Ke YangDepartment of Neurology, Yijishan Hospital, Wannan Medical College, 2# Zheshan West Road, Wuhu, 241001, Anhui Province, China.
Youqing XuDepartment of Neurology, Yijishan Hospital, Wannan Medical College, 2# Zheshan West Road, Wuhu, 241001, Anhui Province, China.
Lili YuanDepartment of Neurology, Yijishan Hospital, Wannan Medical College, 2# Zheshan West Road, Wuhu, 241001, Anhui Province, China.
Qian YangDepartment of Neurology, Yijishan Hospital, Wannan Medical College, 2# Zheshan West Road, Wuhu, 241001, Anhui Province, China.
Xianjun HuangDepartment of Neurology, Yijishan Hospital, Wannan Medical College, 2# Zheshan West Road, Wuhu, 241001, Anhui Province, China. doctorhuangxj@hotmail.com.
Zhiming ZhouDepartment of Neurology, Yijishan Hospital, Wannan Medical College, 2# Zheshan West Road, Wuhu, 241001, Anhui Province, China. neuro_depar@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeThe purpose of our study was to analyse endovascular treatment (EVT) in patients presenting acute anterior circulation ischemic stroke with large-vessel occlusion (AIS-LVO) during the pandemic and post-epidemic periods.

methodsPatients with AIS-LVO of the anterior circulation who underwent EVT were enrolled. According to the times of Wuhan closure and reopening, patients were divided into a pre-pandemic group (from November 8, 2019, to January 22, 2020), pandemic group (from January 23, 2020, to April 8, 2020) and post-epidemic group (from April 9, 2020, to June 24, 2020). The primary endpoints were the time delay among symptom onset to arriving hospital door, to groining puncture and to vascular reperfusion. Secondary endpoints were the functional outcomes evaluated by 90-day modified Rankin scale (mRS) score.

resultsIn total, the times from onset to reperfusion (OTR, median 356 min vs. 310 min, p = 0.041) and onset to door (OTD, median 238 min vs. 167 min, p = 0.017) were prolonged in the pandemic group compared to the pre-pandemic group, and the delay continue in the post-epidemic period. In the subgroup analysis, the time from door to imaging (DTI) was significantly prolonged during the pandemic period. Interestingly, the prolonged DTI was corrected in the directly admitted subgroup during post-epidemic period. In addition, the functional outcomes showed no significant differences across the three periods.

conclusionsTotal time and prehospital time were prolonged during the pandemic and post-epidemic periods. Urgent public education and improved in-hospital screening processes are necessary to decrease time delays.

Indexed as

COVID-19AgedAged, 80 and overBrain IschemiaEndovascular ProceduresFemaleHumansIschemic StrokeMaleMiddle AgedReperfusionRetrospective StudiesTreatment OutcomeAcute ischaemic strokeCOVID-19Endovascular treatmentPandemicPost-epidemic

Identifiers

PMID34167467
PMCPMC8222699

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.