Evidence map›Paper›PMID 34167443›Full record

ArticleVirulence2021

Genetic architecture of transmission stage production and virulence in schistosome parasites.

Winka Le Clec'h, Frédéric D Chevalier, Marina McDew-White, Vinay Menon, Grace-Ann Arya, Timothy J C Anderson

Open access · goldAbstract read
In one paragraph

Article in Virulence, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
5.9field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 34 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Winka Le Clec'hTexas Biomedical Research Institute, San Antonio, Texas, USA.ORCID 0000-0002-1111-2492
Frédéric D ChevalierTexas Biomedical Research Institute, San Antonio, Texas, USA.ORCID 0000-0003-2611-8106
Marina McDew-WhiteTexas Biomedical Research Institute, San Antonio, Texas, USA.ORCID 0000-0001-7821-260X
Vinay MenonTexas Biomedical Research Institute, San Antonio, Texas, USA.
Grace-Ann AryaTexas Biomedical Research Institute, San Antonio, Texas, USA.
Timothy J C AndersonTexas Biomedical Research Institute, San Antonio, Texas, USA.ORCID 0000-0002-0191-0204
Texas Biomedical Research Institute · US

Funding

The Southwest National Primate Research Center Supplement- Infrastructure improvements of ABSL2 holding areasP51OD011133 · OD · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI Larry S. Schlesinger · 2012 to 2026
$129.7M
Genetic Basis of Praziquantel ResistanceR01AI123434 · NIAID · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI ANDERSON, TIM J, LOVERDE, PHILIP T · 2016 to 2020
$3.5M
Genetic analysis of cercarial release in schistosomesR01AI133749 · NIAID · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI ANDERSON, TIM J · 2017 to 2021
$2.5M
Genetic Analysis of Host Specificity in Schistosoma mansoniR01AI097576 · NIAID · TEXAS BIOMEDICAL RESEARCH INSTITUTE · PI ANDERSON, TIM J · 2012 to 2014
$1.7M
MOLECULAR AND BIOCHEMICAL GENETICS LABORATORY RENOVATIONC06RR013556 · NCRR · SOUTHWEST FOUNDATION FOR BIOMEDICAL RES · PI SHADE, ROBERT E · 1998 to 1998
–
NCRR NIH HHS C06 RR013556NIAID NIH HHS R01 AI097576NIAID NIH HHS R01 AI123434NIAID NIH HHS R01 AI133749NIH HHS P51 OD011133
6 · The paper itself

Abstract

Both theory and experimental data from pathogens suggest that the production of transmission stages should be strongly associated with virulence, but the genetic bases of parasite transmission/virulence traits are poorly understood. The blood fluke

Indexed as

BiomphalariaQuantitative Trait LociVirulenceAnimalsCercariaHost-Parasite InteractionsMultifactorial InheritanceSchistosoma mansonibiomphalaria snail hostgenetic crosseslife history traitsquantitative trait loci (qtl)Schistosoma parasitetransmissionvirulence

Identifiers

PMID34167443
PMCPMC8237990
OpenAlexW3174206451

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.