Evidence map›Paper›PMID 34167422›Full record

ReviewJournal of enzyme inhibition and medicinal chemistry2021

Application of triazoles in the structural modification of natural products.

Hong-Yan Guo, Zheng-Ai Chen, Qing-Kun Shen, Zhe-Shan Quan

Open access · goldAbstract readReview
In one paragraph

Review in Journal of enzyme inhibition and medicinal chemistry, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
7.2field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 101 citations in OpenAlex.

  1. Review
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  3. Genomic insights into three Bacillus strains for biocontrol of tobacco black shank disease.International microbiology : the official journal of the Spanish Society for Microbiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Hong-Yan GuoKey Laboratory of Natural Medicines of the Changbai Mountain, Affifiliated Ministry of Education, College of Pharmacy, Yanbian University, Affiliated Hospital of Yanbian University, Yanji, Jilin, China.
Zheng-Ai ChenDepartment of Pharmacology, Medical School of Yanbian University, Yanji, Jilin, China.
Qing-Kun ShenKey Laboratory of Natural Medicines of the Changbai Mountain, Affifiliated Ministry of Education, College of Pharmacy, Yanbian University, Affiliated Hospital of Yanbian University, Yanji, Jilin, China.
Zhe-Shan QuanDepartment of Pharmacology, Medical School of Yanbian University, Yanji, Jilin, China.
Yanbian University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nature products have been extensively used in the discovery and development of new drugs, as the most important source of drugs. The triazole ring is one of main pharmacophore of the nitrogen-containing heterocycles. Thus, a new class of triazole-containing natural product conjugates has been synthesised. These compounds reportedly exert anticancer, anti-inflammatory, antimicrobial, antiparasitic, antiviral, antioxidant, anti-Alzheimer, and enzyme inhibitory effects. This review summarises the research progress of triazole-containing natural product derivatives involved in medicinal chemistry in the past six years. This review provides insights and perspectives that will help scientists in the fields of organic synthesis, medicinal chemistry, phytochemistry, and pharmacology.

Indexed as

Biological ProductsCell Line, TumorChemistry, PharmaceuticalHumansMicrobial Sensitivity TestsMolecular StructureStructure-Activity RelationshipTriazolesBiological ProductsTriazolesbiological activityNatural productstriazole

Identifiers

PMID34167422
PMCPMC8231395
OpenAlexW3177474861

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.