Evidence map›Paper›PMID 34167406›Full record

ArticleApplied neuropsychology. Adult

Association between personality and cognitive performance in middle-aged and older adults with human immunodeficiency virus (HIV).

Pariya L Fazeli, John D Cheatwood, Cierra Hopkins, David E Vance, Maria R Shirey, Andres Azuero, Michael Crowe

Open access · greenAbstract read
In one paragraph

Article in Applied neuropsychology. Adult. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Pariya L FazeliSchool of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.ORCID 0000-0001-6629-0010
John D CheatwoodSchool of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.ORCID 0000-0002-9058-805X
Cierra HopkinsSchool of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.
David E VanceSchool of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.ORCID 0000-0002-0498-6263
Maria R ShireySchool of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.
Andres AzueroSchool of Nursing, University of Alabama at Birmingham, Birmingham, AL, USA.
Michael CroweDepartment of Psychology, University of Alabama at Birmingham, Birmingham, AL, USA.
University of Alabama at Birmingham · US

Funding

Unsolicited R24 for the CFAR-Network of Integrated Clinical Sciences, CNICSR24AI067039 · NIAID · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Michael S. Saag · 2006 to 2026
$99.4M
Pilot CoreP30AG022838 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI BALL, KARLENE K · 2003 to 2020
$5.7M
An RCT of Speed of Processing Training in Middle-Aged and Older Adults with HIVR01MH106366 · NIMH · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI VANCE, DAVID E · 2016 to 2020
$2.6M
A Novel Neurorehabilitation Approach for Cognitive Aging with HIVR00AG048762 · NIA · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WHEELER, PARIYA FAZELI · 2016 to 2018
$747k
Individualized-Targeted Cognitive Training in Older Adults with HANDR21NR016632 · NINR · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI VANCE, DAVID E · 2017 to 2018
$408k
NIAID NIH HHS R24 AI067039NIA NIH HHS P30 AG022838NIA NIH HHS R00 AG048762NIMH NIH HHS R01 MH106366NINR NIH HHS R21 NR016632
6 · The paper itself

Abstract

backgroundNearly half of adults with human immunodeficiency virus (HIV) experience HIV-Associated Neurocognitive Disorder (HAND), characterized by cognitive impairments in two or more cognitive domains, which can interfere with everyday functioning. Many factors are thought to influence such cognitive impairments in adults with HIV; one factor seldom examined is personality.

objectiveThis study investigated the association between five major dimensions of personality (openness, conscientiousness, extraversion, agreeableness, and neuroticism) and cognitive function in older adults with HIV.

methodsIn this cross-sectional study, a secondary data analysis was conducted on 261 HIV + participants. Participants completed a norm-based cognitive battery covering seven cognitive domains, which yielded the following indices: global cognitive impairment, and global and domain-specific T-scores. The Big Five Inventory was used to assess personality traits.

resultsHigher openness, conscientiousness, and agreeableness were associated with better performance on individual cognitive domains while agreeableness and openness were also positively associated with global cognitive T-scores ( DISCUSSION: Openness was associated with better global cognitive function in persons with HIV. This study provides a basis for further investigation of potential mechanisms for the association between personality and cognition in people with HIV in order to ultimately inform intervention strategies.

Indexed as

HIV InfectionsPersonalityAgedCognitionCross-Sectional StudiesHumansMiddle AgedPersonality InventoryAgreeablenessconscientiousnessextraversionglobal cognitionHIV-associated neurocognitive disorderneuroticismopenness

Identifiers

PMID34167406
PMCPMC9045538
OpenAlexW3173404615

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.