Evidence map›Paper›PMID 34167327›Full record

Observational studyStroke2021

Early Brain Injury and Soluble ST2 After Nontraumatic Subarachnoid Hemorrhage.

Riana L Schleicher, Matthew B Bevers, Daniel B Rubin, Matthew J Koch, Søren Bache, India A Lissak, Aman B Patel, Eric S Rosenthal, Kirsten Møller, W Taylor Kimberly

Abstract readLetterObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Stroke, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Riana L SchleicherDivision of Neurocritical Care (R.L.S., D.B.R., I.A.L., E.S.R., W.T.K.), Massachusetts General Hospital, Boston.
Matthew B BeversDivisions of Stroke, Cerebrovascular and Critical Care Neurology, Brigham and Women's Hospital, Boston, MA (M.B.B.).
Daniel B RubinDivision of Neurocritical Care (R.L.S., D.B.R., I.A.L., E.S.R., W.T.K.), Massachusetts General Hospital, Boston.
Matthew J KochDepartment of Neurosurgery (M.J.K., A.B.P.), Massachusetts General Hospital, Boston.
Søren BacheDepartment of Neuroanaesthesiology, Rigshospitalet (S.B., K.M.), University of Copenhagen, Denmark.
India A LissakDivision of Neurocritical Care (R.L.S., D.B.R., I.A.L., E.S.R., W.T.K.), Massachusetts General Hospital, Boston.
Aman B PatelDepartment of Neurosurgery (M.J.K., A.B.P.), Massachusetts General Hospital, Boston.
Eric S RosenthalDivision of Neurocritical Care (R.L.S., D.B.R., I.A.L., E.S.R., W.T.K.), Massachusetts General Hospital, Boston.
Kirsten MøllerDepartment of Neuroanaesthesiology, Rigshospitalet (S.B., K.M.), University of Copenhagen, Denmark.
W Taylor KimberlyDivision of Neurocritical Care (R.L.S., D.B.R., I.A.L., E.S.R., W.T.K.), Massachusetts General Hospital, Boston.

Funding

Neuroscience Resident Research ProgramR25NS065743 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI CASH, SYDNEY S, WILLIAMS, ZIV · 2009 to 2023
$11.8M
Metabolomic predictors of stroke in REGARDSR01NS099209 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI KIMBERLY, WILLIAM TAYLOR · 2017 to 2021
$2.4M
Role of Soluble ST2 in Immune Cell Regulation and Secondary Neurologic Injury After Intracerebral HemorrhageK23NS112474 · NINDS · BRIGHAM AND WOMEN'S HOSPITAL · PI BEVERS, MATTHEW BRADFORD · 2020 to 2024
$1.1M
Real-Time Prediction of Delayed Cerebral Ischemia after Subarachnoid HemorrhageK23NS105950 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI ROSENTHAL, ERIC S. · 2018 to 2022
$1.0M
Therapeutic RNAi treatment for Myotonic DystrophyR61NS112447 · NINDS · UNIVERSITY OF WASHINGTON · PI CHAMBERLAIN, JOEL R · 2020 to 2020
$821k
Brain endothelium and innate immune responses after strokeR21NS120002 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI KIMBERLY, WILLIAM TAYLOR · 2021 to 2021
$451k
NINDS NIH HHS K23 NS105950NINDS NIH HHS K23 NS112474NINDS NIH HHS R01 NS099209NINDS NIH HHS R21 NS120002NINDS NIH HHS R25 NS065743NINDS NIH HHS R61 NS112447
6 · The paper itself

Abstract

[Figure: see text].

Indexed as

BiomarkersBrain InjuriesCohort StudiesHumansInterleukin-1 Receptor-Like 1 ProteinRetrospective StudiesSubarachnoid HemorrhageBiomarkersIL1RL1 protein, humanInterleukin-1 Receptor-Like 1 Proteinbiomarkersbrain injuriesrisk factorssubarachnoid hemorrhage

Identifiers

PMID34167327
PMCPMC8316295

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.