ArticleAnnals of coloproctology2021
Prognostic Factors Affecting Disease-Free Survival and Overall Survival in T4 Colon Cancer.
Article in Annals of coloproctology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed.
- Oncologic outcomes of multivisceral resection for locally advanced colorectal cancer: a single-center retrospective cohort study.BMC surgery · 2025Article
- Prognostic Factors of Postoperative Mortality in Patients with Complicated Right Colon Cancer.Life (Basel, Switzerland) · 2025Article
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- Sorbate metal complexes as newer antibacterial, antibiofilm, and anticancer compounds.BMC microbiology · 2024Article
- Inflammatory Response Markers as Predictors of Colorectal Cancer Prognosis.Ewha medical journal · 2023Review
- Article
- Erratum to "Prognostic factors affecting disease-free survival and overall survival in T4 colon cancer".Annals of coloproctology · 2023Article
- Clinical implication of tissue carcinoembryonic antigen expression in association with serum carcinoembryonic antigen in colorectal cancer.Scientific reports · 2023Article
- Can clinicopathologic high-risk features in T3N0 colon cancer be reliable prognostic factors?Annals of surgical treatment and research · 2023Article
- Prognostic risk factors for pT4 colon cancer: A retrospective cohort study.Oncology letters · 2023Article
- Article
- Molecular Analyses in Peritoneal Metastasis from Colorectal Cancer: A Review-An English Version.Journal of the anus, rectum and colon · 2022Review
Corrections and comments
- Erratum issued
Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeIt is known that as the T stage of a carcinoma progresses, the prognosis becomes poorer. However, there are few studies about factors that affect the prognosis of T4 advanced colon cancer. This study aimed to identify the prognostic factors associated with disease-free survival (DFS) and overall survival (OS) in T4 colon cancer.
methodsPatients diagnosed with stage T4 on histopathology after undergoing curative surgery for colon cancer between March 2009 and March 2018 were retrospectively analyzed for factors related to postoperative survival. Primary outcomes were DFS and OS.
resultsEighty-two patients were included in the study. DFS and OS of the pathologic (p) T4b group were not inferior to that of the pT4a group. Multivariate analysis showed that differentiation (hazard ratio [HR], 4.994; P = 0.005), and laparoscopic surgery (HR, 0.323; P = 0.008) were significant prognostic factors for DFS, while differentiation (HR, 7.904; P ≤ 0.001) and chemotherapy (HR, 0.344; P = 0.038) were significant prognostic factors for OS.
conclusionTumor differentiation, laparoscopic surgery, and adjuvant chemotherapy were found to be significant prognostic factors in patients with T4 colon cancer. Adjuvant chemotherapy and curative resections by laparoscopy might improve the prognosis in these patients.
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