Evidence map›Paper›PMID 34166950›Full record

ArticleEpilepsy & behavior : E&B2021

COVID-19 vaccination in patients with epilepsy: First experiences in a German tertiary epilepsy center.

Randi von Wrede, Jan Pukropski, Susanna Moskau-Hartmann, Rainer Surges, Tobias Baumgartner

Open access · bronzeAbstract read
In one paragraph

Article in Epilepsy & behavior : E&B, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 3 pooled it
3.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 3 syntheses or guidelines pooled it, 53 citations in OpenAlex.

  1. Safety of COVID-19 vaccine in patients with epilepsy: a meta-analysis.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2023
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  20. Impact of COVID-19 vaccine on epilepsy in adult subjects: an Italian multicentric experience.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Randi von WredeDepartment of Epileptology, University Hospital of Bonn, Bonn, Germany. Electronic address: randi.von.wrede@ukbonn.de.
Jan PukropskiDepartment of Epileptology, University Hospital of Bonn, Bonn, Germany.
Susanna Moskau-HartmannDepartment of Epileptology, University Hospital of Bonn, Bonn, Germany.
Rainer SurgesDepartment of Epileptology, University Hospital of Bonn, Bonn, Germany.
Tobias BaumgartnerDepartment of Epileptology, University Hospital of Bonn, Bonn, Germany.
University Hospital Bonn · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionDue to the high demand for information regarding COVID-19 vaccination in people with epilepsy (PWE), we assessed the symptoms and seizure control of PWE following their COVID-19 vaccination.

methodsAll adult patients who were treated at our center were asked to report on their vaccination status and, if vaccinated, about their experiences following their first COVID-19 vaccination with regard to adverse effects and seizure control.

resultsFifty-four PWE have already received their first vaccination against COVID-19 (27 female, 20% seizure free, 96<% on antiseizure medication) and were included in the study. Two-thirds tolerated the vaccines generally either very well or well. Thirty-three percent reported general vaccination adverse effects. The most frequently reported general adverse effects were, in descending order, headache, fatigue and fever, and shivering. With regard to epilepsy-related adverse effects, one patient reported increased seizure frequency one day after the first COVID-19 vaccination was administered, and one reported the occurrence of a new seizure type. None of the patients reported a status epilepticus or aggravation of preexisting adverse effects.

conclusionsOur data suggest that vaccination against COVID-19 appears to be well tolerated in PWE, supporting the recommendation of vaccination to PWE.

Indexed as

COVID-19EpilepsyAdultCOVID-19 VaccinesFemaleHumansSARS-CoV-2VaccinationCOVID-19 VaccinesAdverse effectCOVID-19 pandemicEpilepsySARS-CoV-2Vaccination

Identifiers

PMID34166950
PMCPMC8216683
OpenAlexW3176680091

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.