Evidence map›Paper›PMID 34166610›Full record

ArticleCell chemical biology2021

Intracellular H

Xiaofeng Jiang, Michael R MacArthur, J Humberto Treviño-Villarreal, Peter Kip, C Keith Ozaki, Sarah J Mitchell, James R Mitchell

Open access · greenAbstract read
In one paragraph

Article in Cell chemical biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.6field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 23 citations in OpenAlex.

  1. A universal consuming endogenous HBioactive materials · 2027
    Article
  2. Article
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  5. Article
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  7. A versatile electrochemical, colorimetric, and visible light excitable turn-on fluorescent probe for stress-induced HPhotochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2025
    Article
  8. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Xiaofeng JiangDepartment of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA. Electronic address: xjiang@hsph.harvard.edu.
Michael R MacArthurDepartment of Health Sciences and Technology, ETH Zurich, 8092 Zurich, Switzerland.
J Humberto Treviño-VillarrealDepartment of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA.
Peter KipDepartment of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA; Department of Surgery and the Heart and Vascular Center, Brigham & Women's Hospital and Harvard Medical School, Boston, MA 02115, USA; Einthoven Laboratory for Experimental Vascular Medicine and Department of Surgery, Leiden University Medical Center, 2333 CC Leiden, the Netherlands.
C Keith OzakiDepartment of Surgery and the Heart and Vascular Center, Brigham & Women's Hospital and Harvard Medical School, Boston, MA 02115, USA.
Sarah J MitchellDepartment of Health Sciences and Technology, ETH Zurich, 8092 Zurich, Switzerland. Electronic address: smitchell@ethz.ch.
James R MitchellDepartment of Molecular Metabolism, Harvard T.H. Chan School of Public Health, Boston, MA 02115, USA; Department of Health Sciences and Technology, ETH Zurich, 8092 Zurich, Switzerland.
Harvard University · USBrigham and Women's Hospital · USETH Zurich · CH

Funding

Role of the Mitochondrial Peptide Humanin in Regulating Aging and HealthspanP01AG055369 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI LONGO, VALTER D. · 2018 to 2023
$12.4M
The Role of the Glucose-regulated Protein GRP78/BiP in Stress Resistance and AginP01AG034906 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI LONGO, VALTER D. · 2011 to 2016
$9.3M
Dietary restriction promotes vascular health through hydrogen sulfide-mediated angiogenesisR56AG036712 · NIA · HARVARD SCHOOL OF PUBLIC HEALTH · PI MITCHELL, JAMES R. · 2017 to 2017
$398k
NIA NIH HHS P01 AG034906NIA NIH HHS P01 AG055369NIA NIH HHS R56 AG036712
6 · The paper itself

Abstract

Hydrogen sulfide (H

Indexed as

AnimalsAntineoplastic AgentsAutophagyDNA DamageHeLa CellsHumansHydrogen SulfideMaleMiceMice, Inbred C57BLMice, KnockoutSmall Molecule LibrariesAntineoplastic AgentsHydrogen SulfideSmall Molecule Librariesautophagycancer chemotherapyCGL enzymeDNA damage responsehigh-throughput screeninghydrogen sulfideP3 probeSF7-AM probestress responsesulfide metabolism

Identifiers

PMID34166610
PMCPMC8665944
OpenAlexW3174582487

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.