Evidence map›Paper›PMID 34166603›Full record

ArticleAmerican journal of respiratory cell and molecular biology2021

Smoking and Human Immunodeficiency Virus 1 Infection Promote Retention of CD8

Björn Corleis, Josalyn L Cho, Samantha J Gates, Alice H Linder, Amy Dickey, Antonella C Lisanti-Park, Abigail E Schiff, Musie Ghebremichael, Puja Kohli, Tilo Winkler and 3 more

Open access · greenAbstract read
In one paragraph

Article in American journal of respiratory cell and molecular biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. HIV-associated lung disease.Nature reviews. Disease primers · 2023
    Review
  16. Article
  17. COPD in People with HIV: Epidemiology, Pathogenesis, Management, and Prevention Strategies.International journal of chronic obstructive pulmonary disease · 2023
    Review
  18. Article
  19. Advancing Lung Immunology Research: An Official American Thoracic Society Workshop Report.American journal of respiratory cell and molecular biology · 2022
    Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors at 4 institutions in 2 countries.

Björn CorleisRagon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard, Massachusetts General Hospital and Harvard Medical School, Harvard University, Boston, Massachusetts.ORCID 0000-0001-9833-3169
Josalyn L ChoDivision of Pulmonary, Critical Care and Occupational Medicine, Department of Internal Medicine, College of Medicine, University of Iowa, Iowa City, Iowa.ORCID 0000-0002-0367-4495
Samantha J GatesRagon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard, Massachusetts General Hospital and Harvard Medical School, Harvard University, Boston, Massachusetts.
Alice H LinderRagon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard, Massachusetts General Hospital and Harvard Medical School, Harvard University, Boston, Massachusetts.ORCID 0000-0002-6593-5806
Amy DickeyRagon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard, Massachusetts General Hospital and Harvard Medical School, Harvard University, Boston, Massachusetts.
Antonella C Lisanti-ParkRagon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard, Massachusetts General Hospital and Harvard Medical School, Harvard University, Boston, Massachusetts.
Abigail E SchiffRagon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard, Massachusetts General Hospital and Harvard Medical School, Harvard University, Boston, Massachusetts.ORCID 0000-0002-7233-489X
Musie GhebremichaelRagon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard, Massachusetts General Hospital and Harvard Medical School, Harvard University, Boston, Massachusetts.ORCID 0000-0002-8572-1944
Puja KohliDivision of Pulmonary and Critical Care Medicine, and.
Tilo WinklerDivision of Pulmonary and Critical Care Medicine, and.ORCID 0000-0002-7276-5550
R Scott HarrisDivision of Pulmonary and Critical Care Medicine, and.ORCID 0000-0002-2684-6202
Benjamin D MedoffDivision of Pulmonary and Critical Care Medicine, and.ORCID 0000-0002-2558-0449
Douglas S KwonRagon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard, Massachusetts General Hospital and Harvard Medical School, Harvard University, Boston, Massachusetts.ORCID 0000-0001-8521-8735
Harvard University · USPulmonary and Critical Care Associates · USFriedrich-Loeffler-Institut · DEUniversity of Iowa · US

Funding

Impact of smoking and its cessation on systemic and airway immune activationR01DA042685 · NIDA · BOSTON MEDICAL CENTER · PI LIN, NINA H. · 2016 to 2021
$4.0M
HIV and COPD:Immune mediated mechanismsU01HL121827 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI KWON, DOUGLAS, MEDOFF, BENJAMIN DAVID · 2013 to 2017
$3.2M
NHLBI NIH HHS U01 HL121827NIDA NIH HHS R01 DA042685
6 · The paper itself

Abstract

Smoking and human immunodeficiency virus 1 (HIV-1) infection are risk factors for chronic obstructive pulmonary disease (COPD), which is among the most common comorbid conditions in people living with HIV-1. HIV-1 infection leads to persistent expansion of CD8

Indexed as

AdultBronchoalveolar Lavage FluidCD8-Positive T-LymphocytesChemokine CCL5Chemokine CXCL10ChemotaxisFemaleHIV-1HIV InfectionsHumansMaleMiddle AgedMucous MembranePulmonary Disease, Chronic ObstructiveReceptors, CCR5Receptors, CXCR3CCL5 protein, humanCCR5 protein, humanChemokine CCL5Chemokine CXCL10CXCL10 protein, humanCXCR3 protein, humanReceptors, CCR5Receptors, CXCR3alveolar macrophagesBALchemokineschronic obstructive pulmonary diseaselymphocytes

Identifiers

PMID34166603
PMCPMC8641855
OpenAlexW3176482416

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.